Results 211 to 220 of about 476,829 (342)

Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing

open access: yesAdvanced Genetics, EarlyView.
This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley   +1 more source

Functional Screening of NDUFAF6 Variants in Knockout Cells and Complementary Computational Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We established an ATP‐based functional screening system in NDUFAF6 knockout cells to evaluate the pathogenicity of gene variants associated with mitochondrial dysfunction. Our results highlight the limitations of in silico predictions and underscore the necessity of experimental validation for accurate variant interpretation.
Feng Jiang   +7 more
wiley   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

The bioavailability of selenium in Saccharomyces cerevisiae

open access: gold, 2015
Mona M. Oraby   +2 more
openalex   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni   +6 more
wiley   +1 more source

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