First evolutionary insights into the human otolithic system [PDF]
Communications BiologyThe human otolithic system (utricle and saccule), housed within the bony vestibule of the inner ear, establishes our sense of balance in conjunction with the semicircular canals.
Christopher M. Smith +4 more
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Recording potentials from scala media, saccule and utricle in mice. [PDF]
J Otol, 2015 Liu H, Zhao L.
europepmc +3 more sources
Thirty years with cervical vestibular myogenic potentials: a critical review on its origin [PDF]
Frontiers in NeurologyMyogenic potentials generated by acoustic stimulation of the vestibular system have been reported since 1964. This examination became better known as cervical vestibular evoked myogenic potentials (cVEMPs) and gained increasing clinical application since
Jonas Bruun Kjærsgaard +5 more
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Acute histological reactions in the otolith organs to inner ear drug delivery through a cochlear implant [PDF]
Frontiers in NeurologyIntroductionCochlear implantation is currently regarded as a safe and minimally invasive procedure. However, cochlear implantation can have an impact on vestibular function, despite the lack of correlation between patient symptomatology and damage in ...
Raquel Manrique-Huarte +3 more
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TMC function, dysfunction, and restoration in mouse vestibular organs [PDF]
Frontiers in NeurologyTmc1 and Tmc2 are essential pore-forming subunits of mechanosensory transduction channels localized to the tips of stereovilli in auditory and vestibular hair cells of the inner ear.
Evan M. Ratzan +7 more
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Multifunctional redox modulator prevents blast-induced loss of cochlear and vestibular hair cells and auditory spiral ganglion neurons [PDF]
Scientific ReportsBlast wave exposure, a leading cause of hearing loss and balance dysfunction among military personnel, arises primarily from direct mechanical damage to the mechanosensory hair cells and supporting structures or indirectly through excessive oxidative ...
Dalian Ding +3 more
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Maturation of type I and type II rat vestibular hair cells in vivo and in vitro [PDF]
Frontiers in Cell and Developmental BiologyVestibular sensory epithelia contain type I and type II sensory hair cells (HCI and HCII). Recent studies have revealed molecular markers for the identification of these cells, but the precise composition of each vestibular epithelium (saccule, utricle ...
Mireia Borrajo +15 more
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Matrix recruitment and calcium sequestration for spatial specific otoconia development. [PDF]
PLoS ONE, 2011 Otoconia are bio-crystals anchored to the macular sensory epithelium of the utricle and saccule in the inner ear for motion sensing and bodily balance. Otoconia dislocation, degeneration and ectopic calcification can have detrimental effects on balance ...
Hua Yang +5 more
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Aminoglycoside-induced hair cell death of inner ear organs causes functional deficits in adult zebrafish (Danio rerio). [PDF]
PLoS ONE, 2013 Aminoglycoside antibiotics, like gentamicin, kill inner ear sensory hair cells in a variety of species including chickens, mice, and humans. The zebrafish (Danio rerio) has been used to study hair cell cytotoxicity in the lateral line organs of larval ...
Phillip M Uribe +8 more
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Canonical Wnt Signaling Pathway on Polarity Formation of Utricle Hair Cells
Neural Plasticity, 2021 As part of the inner ear, the vestibular system is responsible for sense of balance, which consists of three semicircular canals, the utricle, and the saccule.
Di Deng +8 more
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