Recording potentials from scala media, saccule and utricle in mice. [PDF]
J Otol, 2015 To describe a protocol for recording electrical potentials from the scala media, saccule, and utricle in mice.CBA/J mice were used and potentials were recorded with glass electrodes inserted through the basilar membrane using a patch clamp system.Resting potentials were successfully recorded from the scala media, saccule and utricle using described ...
Liu H, Zhao L.
europepmc +3 more sources
First evolutionary insights into the human otolithic system [PDF]
Communications BiologyThe human otolithic system (utricle and saccule), housed within the bony vestibule of the inner ear, establishes our sense of balance in conjunction with the semicircular canals.
Christopher M. Smith +4 more
doaj +2 more sources
Thirty years with cervical vestibular myogenic potentials: a critical review on its origin [PDF]
Frontiers in NeurologyMyogenic potentials generated by acoustic stimulation of the vestibular system have been reported since 1964. This examination became better known as cervical vestibular evoked myogenic potentials (cVEMPs) and gained increasing clinical application since
Jonas Bruun Kjærsgaard +5 more
doaj +2 more sources
Matrix recruitment and calcium sequestration for spatial specific otoconia development. [PDF]
PLoS ONE, 2011 Otoconia are bio-crystals anchored to the macular sensory epithelium of the utricle and saccule in the inner ear for motion sensing and bodily balance. Otoconia dislocation, degeneration and ectopic calcification can have detrimental effects on balance ...
Hua Yang +5 more
doaj +1 more source
Aminoglycoside-induced hair cell death of inner ear organs causes functional deficits in adult zebrafish (Danio rerio). [PDF]
PLoS ONE, 2013 Aminoglycoside antibiotics, like gentamicin, kill inner ear sensory hair cells in a variety of species including chickens, mice, and humans. The zebrafish (Danio rerio) has been used to study hair cell cytotoxicity in the lateral line organs of larval ...
Phillip M Uribe +8 more
doaj +1 more source
Canonical Wnt Signaling Pathway on Polarity Formation of Utricle Hair Cells
Neural Plasticity, 2021 As part of the inner ear, the vestibular system is responsible for sense of balance, which consists of three semicircular canals, the utricle, and the saccule.
Di Deng +8 more
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Case Report: Isolated Idiopathic Saccular Dysfunction
Frontiers in Neurology, 2021 Advances in vestibular testing have now allowed us to test each semicircular canal as well as the utricle and saccule, independently. This has led to the discovery of new patterns of vestibular dysfunction that were once impossible to evaluate.
Sofia Waissbluth, Javier Oyarzún
doaj +1 more source
Frontiers in Surgery, 2021 Background: The etiology of Meniere's disease (MD) and endolymphatic hydrops believed to underlie its symptoms remain unknown. One reason may be the exceptional complexity of the human inner ear, its vulnerability, and surrounding hard bone.
Hao Li +7 more
doaj +1 more source
Binocular 3D otolith-ocular reflexes: responses of chinchillas to prosthetic electrical stimulation targeting the utricle and saccule [PDF]
Journal of Neurophysiology, 2020 From animal experiments by Cohen and Suzuki et al. in the 1960s to the first-in-human clinical trials now in progress, prosthetic electrical stimulation targeting semicircular canal branches of the vestibular nerve has proven effective at driving directionally appropriate vestibulo-ocular reflex eye movements, postural responses, and perception.
Kristin N. Hageman +9 more
openaire +2 more sources
Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. [PDF]
PLoS ONE, 2011 Loss-of-function mutations of SLC26A4/pendrin are among the most prevalent causes of deafness. Deafness and vestibular dysfunction in the corresponding mouse model, Slc26a4(-/-), are associated with an enlargement and acidification of the membranous ...
Hyoung-Mi Kim, Philine Wangemann
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