Inner ear morphology in the Atlantic molly Poecilia mexicana--first detailed microanatomical study of the inner ear of a cyprinodontiform species. [PDF]
PLoS ONE, 2011 BACKGROUND: Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Tanja Schulz-Mirbach +2 more
doaj +5 more sources
Age-related changes in the zebrafish and killifish inner ear and lateral line [PDF]
Scientific ReportsAge-related hearing loss (ARHL) is a debilitating disorder for millions worldwide. While there are multiple underlying causes of ARHL, one common factor is loss of sensory hair cells.
Allison B. Coffin +5 more
doaj +2 more sources
Maturation of type I and type II rat vestibular hair cells in vivo and in vitro [PDF]
Frontiers in Cell and Developmental BiologyVestibular sensory epithelia contain type I and type II sensory hair cells (HCI and HCII). Recent studies have revealed molecular markers for the identification of these cells, but the precise composition of each vestibular epithelium (saccule, utricle ...
Mireia Borrajo +15 more
doaj +2 more sources
Irx3/5 Null Deletion in Mice Blocks Cochlea-Saccule Segregation and Disrupts the Auditory Tonotopic Map. [PDF]
J Comp NeurolDeletion mutant of Irx3/5 shows the cochlear base fused with the saccule, whereas in wild‐type mice, the saccule is separated from the base by the ductus reuniens. Irx3 and Irx5 are potential evolutionary branch‐point genes necessary for balance‐sound segregation.
Fritzsch B +7 more
europepmc +2 more sources
Reduced Vestibular Function is Associated With Cortical Surface Shape Changes in the Frontal Cortex. [PDF]
Hum Brain MappWe identified significant cortical surface shape changes in focal areas of the prefrontal cortex that correlate with age‐related vestibular dysfunction in 117 older adults from the Baltimore Longitudinal Study of Aging. These findings provide important insights into mechanisms linking vestibular decline, cognitive impairment, and fall risk in aging ...
Padova D +3 more
europepmc +2 more sources
Matrix recruitment and calcium sequestration for spatial specific otoconia development. [PDF]
PLoS ONE, 2011 Otoconia are bio-crystals anchored to the macular sensory epithelium of the utricle and saccule in the inner ear for motion sensing and bodily balance. Otoconia dislocation, degeneration and ectopic calcification can have detrimental effects on balance ...
Hua Yang +5 more
doaj +1 more source
Aminoglycoside-induced hair cell death of inner ear organs causes functional deficits in adult zebrafish (Danio rerio). [PDF]
PLoS ONE, 2013 Aminoglycoside antibiotics, like gentamicin, kill inner ear sensory hair cells in a variety of species including chickens, mice, and humans. The zebrafish (Danio rerio) has been used to study hair cell cytotoxicity in the lateral line organs of larval ...
Phillip M Uribe +8 more
doaj +1 more source
Canonical Wnt Signaling Pathway on Polarity Formation of Utricle Hair Cells
Neural Plasticity, 2021 As part of the inner ear, the vestibular system is responsible for sense of balance, which consists of three semicircular canals, the utricle, and the saccule.
Di Deng +8 more
doaj +1 more source
Case Report: Isolated Idiopathic Saccular Dysfunction
Frontiers in Neurology, 2021 Advances in vestibular testing have now allowed us to test each semicircular canal as well as the utricle and saccule, independently. This has led to the discovery of new patterns of vestibular dysfunction that were once impossible to evaluate.
Sofia Waissbluth, Javier Oyarzún
doaj +1 more source
Frontiers in Surgery, 2021 Background: The etiology of Meniere's disease (MD) and endolymphatic hydrops believed to underlie its symptoms remain unknown. One reason may be the exceptional complexity of the human inner ear, its vulnerability, and surrounding hard bone.
Hao Li +7 more
doaj +1 more source