Results 11 to 20 of about 2,894 (156)

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei. [PDF]

Dev Dyn
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Lee JH, Yamoah EN, Kersigo J, Elliott K, LaRoda N, Pavlinkova G, Fritzsch B.   +6 more
europepmc   +2 more sources

Developmental Expression of Membrane Pumps and Ion Channels in Human Vestibular Endolymph Homeostasis. [PDF]

Dev Neurobiol
ABSTRACT The expression patterns of key membrane pumps and ion channels involved in endolymph cycling have been studied in the rodent inner ear and the developing and adult human cochlea. However, little is known about their expression during the development of the human vestibular system.
van Beelen ESA, van der Valk WH, de Groot JCMJ, van Benthem PPG, Locher H.   +4 more
europepmc   +2 more sources

Ongoing Discrepancy Between Unilateral Meniere's Disease and Bilateral Endolymphatic Hydrops on Hydrops MRI. [PDF]

Laryngoscope Investig Otolaryngol
ABSTRACT Objective In the era of Hydrops MRI, a clinical dilemma has emerged: while Meniere's disease (MD) is diagnosed unilaterally, Hydrops MRI demonstrates endolymphatic hydrops (EH) bilaterally. This study aims to clarify this ongoing discrepancy. Methods Fifty‐six MD patients underwent an inner ear test battery followed by 3 T Hydrops MRI.
Yang TH, Meng LC, Young YH.
europepmc   +2 more sources

Otopathologic Patterns of Cellular Degeneration in the Peripheral Vestibular Organ Secondary to Head Trauma. [PDF]

Laryngoscope
This study examines vestibular degeneration following head trauma, comparing cases with and without fractures. Histopathological analysis of 26 temporal bones showed more severe damage in nonfracture cases, particularly in Scarpa's ganglion cells and vestibular hair cells.
Shimura T, Takeuchi M, Keskin Yilmaz N, Rajan D, Cureoglu S, Kobayashi S, Monsanto RDC.   +6 more
europepmc   +2 more sources

Advances in otolith-related protein research

Frontiers in Neuroscience, 2022
Otoliths are biological crystals formed by a layer of calcium carbonate crystal that adhere to the ciliary surface of the utricular and saccular receptors in the vestibule of all vertebrates inner ear, enabling the utricle and saccule to better perceive ...
Shouju Huang, Shouju Huang, Shuxia Qian
doaj   +1 more source

Quantitative assessment of inner ear variation in elasmobranchs

Scientific Reports, 2023
Considerable diversity has been documented in most sensory systems of elasmobranchs (sharks, rays, and skates); however, relatively little is known about morphological variation in the auditory system of these fishes.
Derek J. Sauer, Craig A. Radford, Christopher G. Mull, Kara E. Yopak   +3 more
doaj   +1 more source

Morphological analysis of the vestibular system of guinea pigs poisoned by organophosphate

Brazilian Journal of Otorhinolaryngology, 2016
INTRODUCTION: The vestibular system is responsible for body balance. There are substances that damage it, causing dizziness; these are termed vestibulotoxic substances.
Lícia Assunção Cogo, Valdete Alves Valentins dos Santos Filha, Adriana de Andrade Batista Murashima, Miguel Angelo Hyppolito, Aron Ferreira da Silveira   +4 more
doaj   +1 more source

Vestibular modulation of muscle sympathetic nerve activity during sinusoidal linear acceleration in supine humans

Frontiers in Neuroscience, 2014
The utricle and saccular components of the vestibular apparatus detect linear displacements of the head in the horizontal and vertical planes, respectively. We previously showed that sinusoidal linear acceleration in the horizontal plane of seated humans
Elie eHammam, Philip S Bolton, Philip S Bolton, Kenny eKwok, Vaughan G Macefield, Vaughan G Macefield   +5 more
doaj   +1 more source

Validation of inner ear MRI in patients with Ménière’s disease by comparing endolymphatic hydrops from histopathologic specimens

Scientific Reports, 2021
Intravenous gadolinium-enhanced inner-ear magnetic resonance imaging (IV-Gd inner-ear MRI) has been used to visualize endolymphatic hydrops (EH) in clinical diagnosis of Ménière’s disease (MD).
Young Sang Cho, Jong Sei Kim, Min Bum Kim, Sung Min Koh, Chang Hee Lee, Yi-Kyung Kim, Hyung-Jin Kim, Won-Ho Chung   +7 more
doaj   +1 more source

Degeneration of saccular hair cells caused by MITF gene mutation

Neural Development, 2019
Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss.
Yi Du, Li-li Ren, Qing-qing Jiang, Xing-jian Liu, Fei Ji, Yue Zhang, Shuo-long Yuan, Zi-Ming Wu, Wei-Wei Guo, Shi-Ming Yang   +9 more
doaj   +1 more source