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Advances in otolith-related protein research
Otoliths are biological crystals formed by a layer of calcium carbonate crystal that adhere to the ciliary surface of the utricular and saccular receptors in the vestibule of all vertebrates inner ear, enabling the utricle and saccule to better perceive ...
Shouju Huang, Shouju Huang, Shuxia Qian
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Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. [PDF]
Loss-of-function mutations of SLC26A4/pendrin are among the most prevalent causes of deafness. Deafness and vestibular dysfunction in the corresponding mouse model, Slc26a4(-/-), are associated with an enlargement and acidification of the membranous ...
Hyoung-Mi Kim, Philine Wangemann
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Quantitative assessment of inner ear variation in elasmobranchs
Considerable diversity has been documented in most sensory systems of elasmobranchs (sharks, rays, and skates); however, relatively little is known about morphological variation in the auditory system of these fishes.
Derek J. Sauer+3 more
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Morphological analysis of the vestibular system of guinea pigs poisoned by organophosphate
INTRODUCTION: The vestibular system is responsible for body balance. There are substances that damage it, causing dizziness; these are termed vestibulotoxic substances.
Lícia Assunção Cogo+4 more
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Inner ear morphology in the Atlantic molly Poecilia mexicana [PDF]
Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Hess, Martin+2 more
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Intravenous gadolinium-enhanced inner-ear magnetic resonance imaging (IV-Gd inner-ear MRI) has been used to visualize endolymphatic hydrops (EH) in clinical diagnosis of Ménière’s disease (MD).
Young Sang Cho+7 more
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The utricle and saccular components of the vestibular apparatus detect linear displacements of the head in the horizontal and vertical planes, respectively. We previously showed that sinusoidal linear acceleration in the horizontal plane of seated humans
Elie eHammam+5 more
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HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor+4 more
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Degeneration of saccular hair cells caused by MITF gene mutation
Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss.
Yi Du+9 more
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Uneven Effects of Sleep Apnea on Semicircular Canals and Otolithic Organs
ObjectiveThis study aimed to explore how obstructive sleep apnea (OSA) affects the function of each vestibular organ and to identify the correlations among them.MethodsA prospective study was conducted involving 32 healthy controls and 64 patients with ...
Xin-Da Xu+12 more
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