Results 41 to 50 of about 2,887 (163)

Semicircular canal morphology in Rodentia and its relationship to locomotion

Journal of Anatomy, Volume 247, Issue 5, Page 953-969, November 2025.
Here, we present a selection of rodent inner ear 3D models in the lateral view, with rodents from seven locomotor categories (left to right: fossorial, semifossorial, semiaquatic, terrestrial, ricochetal, arboreal, and gliding). Semicircular canal (SCC) morphology, including radius of curvature and shape, can be differentiated between specialized forms
Lily Hou, Ornella C. Bertrand, Hiruni N. Mudannayake, Campbell Rolian, Susanne Cote   +4 more
wiley   +1 more source

Different Contribution of Missense and Loss‐of‐Function Variants to the Genetic Structure of Familial and Sporadic Meniere Disease

MedComm, Volume 6, Issue 10, October 2025.
This study examines the genetic basis of sporadic (SMD) and familial Meniere disease (FMD) by comparing rare protein‐coding variants using exome sequencing and gene burden analysis. FMD patients had a higher accumulation of missense and LoF variants, especially in genes linked to auditory and vestibular function.
Alberto M. Parra‐Perez, Alvaro Gallego‐Martinez, Alba Escalera‐Balsera, Paula Robles‐Bolivar, Patricia Perez‐Carpena, Jose A. Lopez‐Escamez   +5 more
wiley   +1 more source

Firing properties of muscle spindle afferents in the intrinsic foot muscles and tactile afferents from the sole of the foot during upright stance

Experimental Physiology, Volume 110, Issue 10, Page 1492-1510, October 1, 2025.
Abstract We review our approach for undertaking microelectrode recordings from the posterior tibial nerve at the ankle, which has allowed us to identify, for the first time, the firing properties of muscle spindle endings in the intrinsic muscles of the foot and of cutaneous mechanoreceptors in the sole during unsupported standing.
Thomas P. Knellwolf, Alex Burton, Elie Hamman, Vaughan G. Macefield   +3 more
wiley   +1 more source

Skin sympathetic nerve activity is modulated during slow sinusoidal linear displacements in supine humans

Frontiers in Neuroscience, 2016
Low-frequency sinusoidal linear acceleration (0.08 Hz, ±4 mG) modulates skin sympathetic nerve activity (SSNA) in seated subjects (head vertical), suggesting that activation of the utricle in the peripheral vestibular labyrinth modulates SSNA. The aim of
Philip S Bolton, Philip S Bolton, Elie eHammam, Kenny eKwok, Vaughan G Macefield, Vaughan G Macefield   +5 more
doaj   +1 more source

Ageing changes the proprioceptive contribution to balance control under different types of mastoid vibration: A cross‐sectional study

Experimental Physiology, Volume 110, Issue 10, Page 1431-1446, October 1, 2025.
Abstract Ageing‐related sensory deteriorations are significantly associated with poor balance control among older individuals, resulting in a higher risk of falling in a dark environment. In particular, the proprioceptive system plays a critical role in maintaining balance.
Haoyu Xie, Zhuo Wang, Chuhuai Wang, Jung Hung Chien   +3 more
wiley   +1 more source

Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics—A Population‐Level Case‐Control Study

Otolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 613-625, September 2025.
Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li, Rebecca C. Chiffer, Hongyan Li   +2 more
wiley   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

TMC function, dysfunction, and restoration in mouse vestibular organs

Frontiers in Neurology
Tmc1 and Tmc2 are essential pore-forming subunits of mechanosensory transduction channels localized to the tips of stereovilli in auditory and vestibular hair cells of the inner ear.
Evan M. Ratzan, John Lee, Margot A. Madison, Hong Zhu, Wu Zhou, Gwenaëlle S. G. Géléoc, Jeffrey R. Holt, Jeffrey R. Holt   +7 more
doaj   +1 more source

The Efficiency of Simultaneous Binaural Ocular Vestibular Evoked Myogenic Potentials: A Comparative Study with Monaural Acoustic Stimulation in Healthy Subjects [PDF]

Clinical and Experimental Otorhinolaryngology, 2012
ObjectivesTo evaluate the test-retest reliability and convenience of simultaneous binaural acoustic-evoked ocular vestibular evoked myogenic potentials (oVEMP).MethodsThirteen healthy subjects with no history of ear diseases participated in this study ...
Min-Beom Kim, Jae Ho Ban
doaj   +1 more source

Evaluation of the Peripheral Vestibular System due to Inner Ear Barotrauma in the Hyperbaric Environment

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 4, August 2025.
This study investigates changes that may occur in the peripheral vestibular system due to inner ear barotrauma in self‐contained underwater breathing apparatus (SCUBA) divers exposed to hyperbaric environments. Our findings demonstrate that the significant increase in c‐VEMP response amplitudes among SCUBA divers exposed to hyperbaric environments ...
Ömer Bozkurt, Selis Gülseven Güven, Memduha Taş, Şule Yılmaz, Ahmet Köder, Erdoğan Bulut   +5 more
wiley   +1 more source