Results 51 to 60 of about 8,977 (167)

Brucellar arthritis and sacroiliitis: an 8-year retrospective comparative analysis of demographic, clinical, and paraclinical features

Therapeutic Advances in Infectious Disease
Introduction: Brucellosis is a common global zoonotic disease with a wide range of complex and nonspecific clinical manifestations that may lead to misdiagnosis and delayed treatment. Osteoarticular involvement is the most common complaint in brucellosis.
Sanaz Morovati, Arezoo Bozorgomid, Arman Mohammadi, Forouzan Ahmadi, Leila Arghand, Fatemeh Khosravi Shadmani, Babak Sayad   +6 more
doaj   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Sacroiliitis in Children With Familial Mediterranean Fever

, 2019
Cakar, Nilgun/0000-0002-1853-0101; Ozcakar, Zeynep/0000-0002-6376-9189Background/Objective Familial Mediterranean fever (FMF) is an autosomal recessive disease, characterized by recurrent, self-limited attacks of fever with serositis.
Elif Çelikel, Yalcinkaya, Fatos, Acar, Banu Celikel, Z. Birsin Özçakar, Fatoş Yalçinkaya, Banu Çelikel Acar, Aydin, Fatma, Nermin Uncu, Cakar, Nilgun, Celikel, Elif, Ozcakar, Z. Birsin, Nilgün Çakar, Fatma Aydin, Uncu, Nermin   +13 more
core   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Artificial intelligence for the detection of sacroiliitis on magnetic resonance imaging in patients with axial spondyloarthritis

Frontiers in Immunology, 2023
BackgroundMagnetic resonance imaging (MRI) is important for the early detection of axial spondyloarthritis (axSpA). We developed an artificial intelligence (AI) model for detecting sacroiliitis in patients with axSpA using MRI.MethodsThis study included ...
Seulkee Lee, Uju Jeon, Ji Hyun Lee, Seonyoung Kang, Hyungjin Kim, Jaejoon Lee, Myung Jin Chung, Myung Jin Chung, Hoon-Suk Cha   +8 more
doaj   +1 more source

Impact of Dual Interleukin‐17A and Interleukin‐17F Inhibition with Bimekizumab on Inflammatory and Structural Lesions in Axial Spondyloarthritis: MRI and Radiographic Outcomes from the Phase 3 BE MOBILE 1 and 2 Studies and their Open‐Label Extension

Arthritis &Rheumatology, Accepted Article.
Objectives To evaluate the impact of bimekizumab, a dual IL‐17A and IL‐17F inhibitor, on sacroiliac joint (SIJ) and spine inflammation/structural damage in axSpA using MRIs/radiographs from the phase 3 studies BE MOBILE 1 (nr‐axSpA) and 2 (r‐axSpA) and their open‐label extension (OLE).
Walter P. Maksymowych, Sofia Ramiro, Denis Poddubnyy, Xenofon Baraliakos, Robert G.W. Lambert, Ute Massow, Tom Vaux, Chetan Prajapati, Alexander Marten, Natasha de Peyrecave, Mikkel Østergaard   +10 more
wiley   +1 more source

Increased prevalence of pelvic venous congestion sign on sacroiliac MRI in women with clinically suspected sacroiliitis

İstanbul Kuzey Klinikleri, 2020
OBJECTIVE: To compare the prevalence of pelvic venous congestion (PVC) sign on sacroiliac and hip MRI in women of reproductive age as a possible cause of pain mimicking sacroiliitis.
Ahmet Peker, Gozde Tokatli, Ali Balci, Isil Basara Akın, Canan Altay, Gercek Can   +5 more
doaj   +1 more source

The frequency of sacroiliitis in familial Mediterranean fever and the role of HLA-B27 and MEFV mutations in the development of sacroiliitis

, 2009
The objective of this study was to investigate the frequency of sacroiliitis in familial Mediterranean fever (FMF) patients and the role of HLA-B27 and MEFV mutations in the development of sacroiliitis. The study group consisted of 256 FMF patients (male
Calisir, Cueneyt, Cansu, Doendue Ue., KORKMAZ, CENGİZ, KAŞİFOĞLU, TİMUÇİN   +3 more
core   +1 more source

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

Preliminary Validation of the Early Sacroiliitis Screening Tool (ESHST) for Identifying Hidradenitis Suppurativa Patients at High Risk of Spondyloarthritis

International Journal of Dermatology, EarlyView.
Development and preliminary validation of the Early Sacroiliitis Screening Tool (ESHST), a dermatology‐oriented screening questionnaire for identifying hidradenitis suppurativa patients at increased risk of spondyloarthritis. ABSTRACT Background Hidradenitis suppurativa (HS) is increasingly recognized as a systemic inflammatory disease associated with ...
Umut Bakay, Ozge Sevil Karstarli Bakay, Tugba Izci Duran, Niyazi Cetin   +3 more
wiley   +1 more source