Results 81 to 90 of about 262,483 (141)
MicroorganismsSwine acute diarrhea syndrome coronavirus (SADS-CoV) is a recently discovered enteric coronavirus that has caused considerable economic losses in the pig industry.
Chenchen Zhao +11 more
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Ecology and Evolution, Volume 16, Issue 10, October 2026.We present the first whole‐genome assembly for the Trindade petrel (Pterodroma arminjoniana), a wide‐ranging procellariiform seabird of conservation and eco‐evolutionary importance. These resources provide a reference‐quality genome for future studies of taxonomy and systematics, morphology, hybridisation, gene flow, population structure, conservation ...
Mariana Scain Mazzochi +8 more
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Veterinary ResearchSwine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine enteric coronavirus that causes acute watery diarrhea, vomiting, and dehydration in newborn piglets.
Chunhui Zhong +12 more
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Bile acid (BA) promotion of SADS-CoV replication is dependent on lipid rafts.
, 2022 (A) Porcine intestinal enteroid (PIE) monolayers were pretreated with MβCD for 1 h, and then MβCD and cholic acid (CA) were added to the medium at the indicated concentration during and after SADS-CoV-GFP infection for 48 h.
Chan Ding (317445) +9 more
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The Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.Abstract Concentration‐QTc analysis from Phase 1 studies is increasingly used to evaluate QTc prolongation risk as an alternative to thorough QT (TQT) studies. According to International Conference on Harmonization E14 documents, such analyses should include exposures at twice the highest clinically relevant exposure instead of a positive control to ...
Yushi Kashihara +6 more
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, 2022 (A) Porcine intestinal enteroid (PIE) monolayers treated with medium alone or 100 μM cholic acid (CA) for 1 h. Images were acquired by confocal laser-scanning microscopy, detecting Rab5, Rab7 and LAMP1 (green), and nuclei (blue) were visualized by DAPI ...
Chan Ding (317445) +9 more
core +1 more source
Clinical modifiers of the association between type 1 diabetes and dementia incidence
Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.Abstract INTRODUCTION Type 1 diabetes mellitus (T1DM) increases dementia risk. Understanding clinical modifiers of that effect could inform prevention. METHODS We analyzed data from All of Us. Participants were aged ≥50 years with T1DM (n = 5,442) or no diabetes (n = 226,819).
Anna M. Pederson +13 more
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The IRE1-JNK-Beclin 1 signaling pathway is involved in SADS-CoV-induced autophagy.
, 2023 (A) ST cells that untreated or treated with Control siRNA or siIRE1 for 48 h, are infected with SADS-CoV for 36 h. A western blotling analysis is performed with the indicated antibodies.
Jianfei Chen (3186999) +19 more
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Prosocial helping behaviors attenuate accelerated cognitive decline driven by APOE ε4
Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.Abstract INTRODUCTION The apolipoprotein E (APOE) ε4 allele accelerates cognitive decline through multiple biological pathways—including neuroinflammatory, vascular, and stress‐regulatory mechanisms—yet few modifiable behaviors counter this genetic vulnerability.
Sae Hwang Han, Jessica Danielle Faul
wiley +1 more source
Quercetin inhibition of porcine intestinal alpha coronavirus in vitro and in vivo
BMC Veterinary ResearchBackground Porcine acute diarrhea syndrome coronavirus (SADS-CoV) is one of the novel pathogens responsible for piglet diarrhea, contributing to substantial economic losses in the farming sector. The broad host range of SADS-CoV raises concerns regarding
Yongzhi Feng +7 more
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