Results 101 to 110 of about 4,778,747 (305)
Psychological safety and patient safety
Psychological safety is a critical yet often overlooked component in ensuring patient safety within healthcare environments. This paper explores the intrinsic link between psychological safety and patient outcomes, highlighting how a culture of openness, trust, and non-punitive communication can significantly enhance healthcare delivery.
openaire +1 more source
Design-Based Safety: The Evolution of Safety
, 2015 The word “safety” has a variety of meanings. It is a condition of being free from “accidents,” or any device for preventing an accident. The word “accident” means “unintended event,” and does not reveal that there is a cause created by a “hazard.” In ...
MacCollum, David
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
System Safety Bookshelf: Applying Safety Standards to Life-Saving Equipment
, 2019 Elsevier Academic Press has recently published a new safety book titled Safety Risk Management for Medical Devices, written by Bijan Elahi. This book explains how to conduct a risk management program that will show conformance to the FDA safety standards
Ericson, Clif
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Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
, 2014 In January 2013, a two-day Safety Case Workshop was conducted in Huntsville, Alabama under the sponsorship of the SAE International G-48 System Safety Committee and A-P-T Research, Inc. (APT). Attendees from industry, government and academia participated,
McDermid, John +7 more
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
'Technical Safety’ or ‘System Safety’? Why Names Matter [PDF]
, 2014 By providing safety and risk management consulting services, we have the opportunity to be regularly involved with clients from a number of different industries.
Oliva, Sergio, Lopez, Ricardo
core
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source