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Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]
Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
doaj +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Reasoned opinion on the modification of the existing MRLs for quizalofop-P in oilseed rape, sunflower, cotton and soybean [PDF]
In accordance with Article 6 of Regulation (EC) No 396/2005, Spain, hereafter referred to as the evaluating Member State (EMS), received from Nissan Chemical Europe an application to modify the existing MRLs of quizalofop-P in rapeseed, sunflower, cotton
European Food Safety Authority
doaj +1 more source
Foodborne diseases are responsible for 420,000 deaths each year, one-third of them in Africa. Food safety issues are usually attributed to traditional food systems, but the development of modern food systems in low-income (LI) and lower middle-income ...
Figuié, Muriel
core +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Conclusion on the peer review of the pesticide risk assessment of the active substance Isaria fumosorosea strain Apopka 97 (formerly Paecilomyces fumosoroseus Apopka strain 97) [PDF]
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State Belgium, for the pesticide active substance Isaria fumosorosea ...
European Food Safety Authority
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Health risk of ammonium released from water filters [PDF]
<p>The European Commission (EC) asked the European Food Safety Authority (EFSA) for scientific assistance regarding the possible impact on human health of exposure to ammonium released from water filter cartridges. EFSA was asked whether a level of
European Food Safety Authority
doaj +1 more source
A STUDY OF WORK SAFETY BEHAVIOR AT PT. AST INDONESIA SEMARANG [PDF]
The aim of this study is to analyse the effect of Safety Leadership, Safety Culture and Safety Training that influences the employee Safety Behavior at PT. AST Indonesia Semarang.
HERYANTO, Ari +2 more
core

