Results 41 to 50 of about 8,156,460 (356)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]

open access: yesEFSA Journal, 2013
Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Reasoned opinion on the modification of the existing MRLs for quizalofop-P in oilseed rape, sunflower, cotton and soybean [PDF]

open access: yesEFSA Journal, 2012
In accordance with Article 6 of Regulation (EC) No 396/2005, Spain, hereafter referred to as the evaluating Member State (EMS), received from Nissan Chemical Europe an application to modify the existing MRLs of quizalofop-P in rapeseed, sunflower, cotton
European Food Safety Authority
doaj   +1 more source

Food safety risks [PDF]

open access: yes, 2019
Foodborne diseases are responsible for 420,000 deaths each year, one-third of them in Africa. Food safety issues are usually attributed to traditional food systems, but the development of modern food systems in low-income (LI) and lower middle-income ...
Figuié, Muriel
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Conclusion on the peer review of the pesticide risk assessment of the active substance Isaria fumosorosea strain Apopka 97 (formerly Paecilomyces fumosoroseus Apopka strain 97) [PDF]

open access: yesEFSA Journal, 2014
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State Belgium, for the pesticide active substance Isaria fumosorosea ...
European Food Safety Authority
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Health risk of ammonium released from water filters [PDF]

open access: yesEFSA Journal, 2012
<p>The European Commission (EC) asked the European Food Safety Authority (EFSA) for scientific assistance regarding the possible impact on human health of exposure to ammonium released from water filter cartridges. EFSA was asked whether a level of
European Food Safety Authority
doaj   +1 more source

A STUDY OF WORK SAFETY BEHAVIOR AT PT. AST INDONESIA SEMARANG [PDF]

open access: yes, 2017
The aim of this study is to analyse the effect of Safety Leadership, Safety Culture and Safety Training that influences the employee Safety Behavior at PT. AST Indonesia Semarang.
HERYANTO, Ari   +2 more
core  

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