Results 51 to 60 of about 5,523,377 (316)
Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance ethoprophos [PDF]
EFSA Journal, 2013 The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State the United Kingdom, for the pesticide active substance ethoprophos
European Food Safety Authority
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FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Reasoned opinion on the review of the existing maximum residue levels (MRLs) for fluoxastrobin according to Article 12 of Regulation (EC) No 396/2005 [PDF]
EFSA Journal, 2012 According to Article 12 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) has reviewed the Maximum Residue Levels (MRLs) currently established at European level for the pesticide active substance fluoxastrobin.
European Food Safety Authority
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Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Acknowledgement to Reviewers of Safety in 2018
Safety, 2019 Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Safety Editorial Office
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Reasoned opinion on the review of the existing maximum residue levels (MRLs) for propargite according to Article 12 of Regulation (EC) No 396/2005 [PDF]
EFSA Journal, 2013 According to Article 12 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) has reviewed the Maximum Residue Levels (MRLs) currently established at European level for the pesticide active substance propargite.
European Food Safety Authority
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Efficacy and safety of alirocumab in reducing lipids and cardiovascular events.
New England Journal of Medicine, 2015 BACKGROUND Alirocumab, a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9), has been shown to reduce low-density lipoprotein (LDL) cholesterol levels in patients who are receiving statin therapy.
Jennifer G. Robinson +15 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Patient Safety, 2023 The spring 2023 issue of *Patient Safety* is available to read and download at no charge. This issue features four articles that came out of the Patient Safety Authority’s first master class in writing quality improvement studies.
Patient Safety Authority
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