Results 131 to 140 of about 3,131,593 (360)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Adolescent road user behaviour : a survey of 11-16 year olds [PDF]
, 2003 This study was carried out to investigate the safety related behaviour of road users aged 11-16. A self-completion questionnaire was designed to measure the frequency with which children from the target population carry out 43 different road using ...
Baughan, C.J. +2 more
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Digital manufacturing in fiat group automobiles: virtual simulations for preliminary ergonomics optimization of workcells in the design phase of a new car model [PDF]
, 2013 New standards on work organization in the automotive industry, require a new concept of design methods: the human centred process. In Fiat Group Automobiles (FGA) the “Digital Manufacturing” (DM) project has started with the goal to create simulation ...
Frascà, Fabrizio +2 more
core
Efficacy and Safety of Tumor Necrosis Factor Antagonists in Crohn's Disease: Meta-Analysis of Placebo-Controlled Trials [PDF]
, 2008 Laurent Peyrin‐Biroulet +5 more
openalex +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Strength and Deformation of Pillars during Mining in the Shaft Pillar
Applied SciencesThis study of the strength and deformation of coal samples was triggered by the need to define the stress–strain characteristics of pillars during room and pillar mining in the shaft protective pillar at the ČSM Mine.
Jindřich Šancer +3 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Hetero-bonding strength investigation into opto-mechanical interface
Frontiers in Astronomy and Space SciencesGlass-metal hetero-bonding through optical epoxy adhesive is frequently used in opto-mechanics and requires high stability. However, the bonding stability is difficult to achieve and predict in massive use cases, where dozens to thousands of metal pads ...
Haifei Hu +4 more
doaj +1 more source