Results 81 to 90 of about 1,108,809 (316)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Patient safety in health care professional educational curricula: examining the learning experience
, 2009 This study has investigated the formal and informal ways pre-registration students from four healthcare professions learn about patient safety in order to become safe practitioners.
Steven, Alison +2 more
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Evaluation study of IEEE 1609.4 performance for safety and non-safety messages dissemination
, 2014 The IEEE 1609.4 was developed to support multi-channel operation and channel switching procedure in order to provide both safety and non-safety vehicular applications.
Alaa, Mina +2 more
core
Health and safety of the older worker [PDF]
, 2012 This is the author's pre-copyedited accepted manuscript. The final published article is available from the link below. Copyright @ 2012 The Authors.Background - In the UK, increasing numbers of paid employees are over 60 years with further increases ...
Farrow, A, Reynolds, F
core +1 more source
Identifying NPP operator stressors using grounded theory
Scientific ReportsNuclear power plant (NPP) operators manage crucial decision-making and operational tasks in precarious and complex environments, where psychological stress directly correlates with system safety and operational efficiency.
Ye Wang +4 more
doaj +1 more source
GeotechnicsBioengineering techniques are being increasingly adopted as a sustainable solution to soil slope instability. Despite their recognized benefits, however, the mechanistic contribution of vegetation to slope stability remains inadequately understood due to
Ram Chandra Tiwari +1 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
BuildingsSince the stability of slopes in infrastructures such as road and railroad embankments, excavations, and, in general, earthwork is important, analyzing the stability of these slopes has been one of the main focuses of geotechnical engineers.
SeyedSaber Hosseini +4 more
doaj +1 more source
Cardiac Factors of Safety [PDF]
Circulation Research, 1953 R S, ALEXANDER, C J, WIGGERS
openaire +2 more sources