Results 101 to 110 of about 20,641,169 (265)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Adaptive Multi-Point Temperature Control for Microwave Heating Process via Multi-Rate Sampling

SICE Journal of Control, Measurement, and System Integration, 2019
Microwave heating has been gradually extended to industrial material process from domestic microwave ovens because of its substantial advantages such as high-efficiency, pollution free, and selective heating.
Shan Liang, Tong Liu, Junrong Song, Qingyu Xiong, Kai Wang   +4 more
doaj   +1 more source

Improvement of the occupational risk management process in the work safety system of the enterprise. [PDF]

Front Public Health, 2023
Bazaluk O, Tsopa V, Okrasa M, Pavlychenko A, Cheberiachko S, Yavorska O, Deryugin O, Lozynskyi V.   +7 more
europepmc   +1 more source

System Safety in Healthcare: Electronic Health Records: Dangers for Patient Safety

, 2015
Electronic health records (EHR) are critical to precision medicine. They provide greater patient access to medical history data and are available quickly. But there are many inherent risks in using these records.
Escano, Maria, Raheja, Dev
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Notes on Society History: Pathfinders of System Safety

, 2014
The beginnings of “organized, formally documented” system safety occurred during the years 1956 to 1966. The origins of the System Safety Concept (SSC) are summarized in “Historical Note No.
Rex
core  

Notes on Society History: The Early Dissemination of System Safety Concepts and Techniques

, 2015
Members of the International System Safety Society (ISSS) are familiar with the excellent articles, papers and updates published in this Journal, and with the annual ISSS Conferences/Symposia held each summer at various locations in the U.S.
Gordon, Rex
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Evaluation of temperatures and flow areas of the Phebus Test FPT0

Nuclear Engineering and Technology
The cladding temperatures and axial mass distribution computed by MAAP5 were compared with their measured values in the test bundle of the Phebus Test FPT0.
Koji Nishida, Naoki Sano, Seitaro Sakurai, Michio Murase   +3 more
doaj   +1 more source