Results 71 to 80 of about 403,434 (220)

Evidence for Drop‐Like Nuclear Deformation in Sheared Endothelial Monolayers

Small, EarlyView.
Physiological shear stress smoothens endothelial monolayers by selectively eliminating less‐spread cells with tall, wrinkled nuclei. Nuclear volume and surface area remain constant, consistent with drop‐like deformation governed by geometric constraints.
Mohammad Mohajeri, Ting‐Ching Wang, Pooja Agarwal, Simran Kaur, Ankit Kumar, Richard B. Dickinson, Abhishek Jain, Tanmay P. Lele   +7 more
wiley   +1 more source

Step‐Ladder Bioprinting to Align Collagen Fibers for Anisotropic Tissue Fabrication

Small, EarlyView.
The step‐ladder printing platform includes successive segments of channels with varying widths in a custom barrel design. This design allows for improved anisotropy of collagen fibers during extrusion. To demonstrate its effectiveness, corneal constructs with high transparency and shape fidelity, as well as articular cartilage constructs, displaying ...
Ilayda Namli, Yogendra Pratap Singh, Deepak Gupta, Syed Hasan Askari Rizvi, Yasar Ozer Yilmaz, Joao Vitor Silva Robazzi, Medine Dogan Sarikaya, Mehmet Baykara, Ibrahim T. Ozbolat   +8 more
wiley   +1 more source

Kinship through code, personhood as node: AI afterlives and new technologies of the self Parenté par le code, personne nodale : vie posthume dans l'IA et nouvelles technologies du moi

Journal of the Royal Anthropological Institute, EarlyView.
This article examines how emerging generative AI technologies in Europe and North America are being used to reanimate the dead, prompting users to define the ‘edges’ of self and personhood through coding practices. These technologies invite new engagements with fundamental questions of relatedness and the construction of the self, challenging and ...
Jennifer Cearns
wiley   +1 more source

How to Imagine Educational AI: The Filling of a Pail or the Lighting of a Fire?

Educational Theory, EarlyView.
Abstract Recent advances in artificial intelligence (e.g., machine learning, generative AI) have led to increased interest in its application in educational settings. AI companies hope to revolutionize teaching and learning by tailoring material to the individual needs of students, automating parts of teachers' jobs, or analyzing educational data to ...
Michał Wieczorek, Alberto Romele
wiley   +1 more source

On Schopenhauer's Debt to Spinoza1

European Journal of Philosophy, EarlyView.
Abstract Schopenhauer offers ‘nature is not divine but demonic’ as a direct rebuttal of Spinoza's pantheism, his identification of ‘nature’ with ‘God’. And so, one would think, he ought to have been immune to the ‘Spinozism’ that became, as Heine called it, ‘the unofficial religion’ of the age.
Julian Young
wiley   +1 more source

The Long Wait (Part I): A Personal Account of Infantry Training in Britain, June 1942–June 1943 [PDF]

, 2012
In the early summer of 1942, Harold (Hal) MacDonald, a young infantry officer from Saint John, New Brunswick, was posted overseas to join the North Shore (New Brunswick) Regiment, then stationed in Great Britain.
MacDonald, Harold, MacDonald, M.A.
core   +2 more sources

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

The FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott, Jui‐Hung Weng, Valeria Pane, Yuliang Ma, Jian Wu, Susan S. Taylor, Friedrich W. Herberg   +6 more
wiley   +1 more source

Biography and cinema in History of Education: aspects of the teaching profession in the movie movie ‘Saint John Baptist de La Salle: patron saint of teachers’

, 2018
Este artigo aborda, a partir do filme São João Batista de La Salle: padroeiro dos professores, os caminhos da profissão docente no século XVII, destacando a presença da Igreja nesse cenário e o método simultâneo utilizado pela congregação dos Irmãos das Escolas Cristãs. Temos como objetivo pensar o filme como fonte e objeto para a História da Educação,
openaire   +1 more source

‘QUOD NON EST IN BEROLINA, NON EST IN MUNDO’: VIEWS FROM THE PERIPHERY

German Life and Letters, EarlyView.
ABSTRACT The historiography of Weimar cinema has focused almost exclusively on film production and exhibition in the German capital Berlin, generally neglecting other geographic regions, in particular the Rhineland which, after the First World War, remained under Allied control until the mid‐1920s for some parts, for others even longer.
Frank Kessler, Sabine Lenk
wiley   +1 more source