Results 71 to 80 of about 2,188 (182)

Cryo-EM structure of African horse sickness virus VP2 receptor-binding protein enables nanoparticle vaccine design. [PDF]

open access: yesNat Commun
Martínez-Castillo A   +17 more
europepmc   +1 more source

Cannabis consumption and problematic internet use: analysis of a free-text response collected through a self-reported online questionnaire. [PDF]

open access: yesBMC Psychol
St-Onge J   +10 more
europepmc   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

open access: yesThe FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti   +11 more
wiley   +1 more source

Longitudinal Single-Axon-Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant. [PDF]

open access: yesAdv Sci (Weinh)
Luzhansky ID   +15 more
europepmc   +1 more source

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

open access: yesThe FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal   +4 more
wiley   +1 more source

Prevalence and Determinants of Nomophobia Among Healthcare Workers in Nepal: A Cross-Sectional Study. [PDF]

open access: yesCureus
Banjade P   +7 more
europepmc   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

open access: yesThe FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli   +6 more
wiley   +1 more source

Disrupting Dominant Ideologies in Chilean Teacher Education Through Ideological Clarity

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This study seeks to develop a more nuanced understanding of how English language teacher educators navigate the tensions between and across institutional expectations, the Chilean sociopolitical landscape, the increasing diversity and their pedagogical choices as they construct their professional identities.
Leonardo Veliz, Flor Toledo‐Sandoval
wiley   +1 more source

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