Results 61 to 70 of about 277,402 (313)
Stars and saints: professional conversations for enhancing classroom practices [PDF]
, 2016 This paper explores a reflective activity - professional conversation. In so doing, it recalls the recent experience of working alongside 'starring' teachers who are dedicated to serving the poor in areas of deprivation.
Luby, Antony
core +3 more sources
ADLFI. Archéologie de la France - Informations, 2007 Identifiant de l'operation archeologique : 025378 Date de l'operation : 2008 (SU) Decouvert par prospection de surface, le site voisinait les travaux de construction d’un petit supermarche. Les degâts etaient deja faits, neanmoins un locusdonnant des tessons de ceramique medievale en grande quantite semblait persister au-dela du fosse de ceinture de la
Marache, Valérie +2 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Theological Creative Nonfiction: Christian Literature for Christian Life [PDF]
, 2014 Since the Christian worldview is composed of more than theoretical truth, Christian literature should reflect these other aspects, such as how that truth is applied in the lives of the saints.
Hurt, Elizabeth R
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Linked Data Authorization Platform
IEEE Access, 2018 The expansion of the smart devices, the growing popularity of the social networks, and the wide spread of the corporate services impose huge amounts of heterogeneous data to be generated and stored in separate silos on a daily basis.
Riste Stojanov +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Colleen Carroll Campbell: Catholicism, Feminism, and Women Saints [PDF]
, 2014 Many views of modern day feminism appear to contradict the teachings of the Catholic Church. However, Colleen Carroll Campbell, an award-winning author and journalist, was determined from a young age to reconcile feminism with Catholicism.
Dulmaine, Hannah
core +1 more source