Results 31 to 40 of about 1,480 (172)

Cardio-protection of salvianolic acid B through inhibition of apoptosis network.

open access: yesPLoS ONE, 2011
Targeting cellular function as a system rather than on the level of the single target significantly increases therapeutic potency. In the present study, we detect the target pathway of salvianolic acid B (SalB) in vivo.
Lingling Xu   +13 more
doaj   +1 more source

Thermodynamic Modeling of Solvent-Assisted Lipid Bilayer Formation Process

open access: yesMicromachines, 2022
The solvent-assisted lipid bilayer (SALB) formation method provides a simple and efficient, microfluidic-based strategy to fabricate supported lipid bilayers (SLBs) with rich compositional diversity on a wide range of solid supports.
Hongmei Xu   +4 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

Salvianolic Acid B Improves Mitochondrial Function in 3T3-L1 Adipocytes Through a Pathway Involving PPARγ Coactivator-1α (PGC-1α)

open access: yesFrontiers in Pharmacology, 2018
Purpose: Mitochondrial dysfunction in adipose tissue has emerged as key to the development of obesity and diabetes. Salvianolic acid B (SalB) is a water-soluble ingredient derived from Salvia miltiorrhiza that has been shown to possess potential anti ...
Yanyun Pan   +22 more
doaj   +1 more source

Salvianolic Acid B Strikes Back: New Evidence in the Modulation of Expression and Activity of Matrix Metalloproteinase 9 in MDA-MB-231 Human Breast Cancer Cells

open access: yesMolecules, 2022
Salvianolic acid B (SalB) is a bioactive compound from Salviae miltiorrhizae, one of the most important traditional herbal medicines widely used in several countries for the treatment of cardiovascular diseases.
Andrea Ianni   +6 more
doaj   +1 more source

S3‐Leitlinie Diagnostik und Therapie der Alopecia areata – Teil 2: Therapie, psychosoziale und kosmetische Unterstützung

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1155-1179, August 2026.
Zusammenfassung In diesem zweiten Teil der S3‐Leitlinie zur Diagnostik und Therapie der Alopecia areata (AA) stellen wir die zentralen Inhalte und Empfehlungen zur topischen und systemischen Therapie, zur Lebensqualität und zu Unterstützungsangeboten vor.
Ulrike Blume‐Peytavi   +13 more
wiley   +1 more source

Association Between Serum Albumin Level and Microvascular Complications of Type 2 Diabetes Mellitus

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Jie Zhang,1 Yuanyuan Deng,1 Yang Wan,1 Shasha He,1 Wei Cai,2 Jixiong Xu1,3,4 1Department of Endocrinology and Metabolism, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 2Department of Medical ...
Zhang J   +5 more
doaj  

Salvianolic Acid B Upregulates miR‐744‐5p Expression in Peripheral Blood Mononuclear Cell–Derived Extracellular Vesicles to Alleviate Uremic Cardiomyopathy

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Uremic cardiomyopathy (UCM) is a life‐threatening complication of uremia. We find that extracellular vesicle (EV)‐miR‐744‐5p mediates peripheral blood mononuclear cell (PBMC)‐cardiomyocyte communication in UCM. Salvianolic acid B treats UCM by modulating EV‐miR‐744‐5p expression.
Ziran Wang   +17 more
wiley   +1 more source

Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice.

open access: yesPLoS ONE, 2016
BackgroundHeart failure(HF) is a dangerous disease that affects millions of patients. Radix Salvia is widely used in Chinese clinics to treat heart diseases. Salvianolic acid B(SalB) is the major active component of Radix Salvia.
Juan Yu   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy