Results 21 to 30 of about 2,338 (206)

Salvianolic Acid B Alleviates MAFLD by Targeting PPAR-α: Mechanistic Insights From Network Pharmacology and Lipidomics. [PDF]

Food Sci Nutr
Salvianolic acid B (SALB) is the major water‐soluble bioactive constituent of Salvia miltiorrhiza Bunge, a traditional Asian health‐promoting food, while its therapeutic potential and molecular mechanisms in the pathogenesis of MAFLD remain largely unclear.
Huang F, Qiu C, Wang D, Ni Y, Fu Z, Fu L, Liang C, Huang S, Deng Z.   +8 more
europepmc   +2 more sources

Structure and composition of supported lipid bilayers: a comparison between solvent-assisted lipid bilayer and vesicle fusion methods. [PDF]

J Appl Crystallogr
Neutron reflectometry is used to compare supported lipid bilayers formed by vesicle fusion and solvent‐assisted lipid bilayer (SALB) methods, revealing structurally comparable architectures with minor differences in acyl chain thickness and low residual solvent incorporation.
Felderer B, Buchanan C, Wang S, Shen HH, Nelson A, Hall SCL, Cárdenas M.   +6 more
europepmc   +2 more sources

Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage

Frontiers in Immunology, 2023
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a critical role in exacerbating early brain injury (EBI) after subarachnoid hemorrhage ...
Dayong Xia, Jinlong Yuan, Degang Wu, Haibin Dai, Zong Zhuang   +4 more
doaj   +1 more source

An In Situ Embedded B-MOF Sponge With Shape-Memory for All-in-One Diabetic Wound Therapy. [PDF]

Adv Healthc Mater
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Zhou H, Huang C, Chen Y, Zhao T, Zhu F, Jun G, Zhang J, Pan Y, Wen Q, Yang L, Zhang H, Chen L.   +11 more
europepmc   +2 more sources

Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway

Pharmaceutical Biology, 2022
Context Salvianolic acid B (SalB) can attenuate myocardial ischemia/reperfusion (I/R) injury, but the mechanisms are not entirely known.Objective Our study investigates if SalB protects cardiomyocytes against I/R injury by regulating Tripartite motif ...
Bo Lu, Jianhua Li, MingTai Gui, Lei Yao, Mingsong Fan, Xunjie Zhou, Deyu Fu   +6 more
doaj   +1 more source

The Salvinorin Analogue, Ethoxymethyl Ether Salvinorin B, Promotes Remyelination in Preclinical Models of Multiple Sclerosis

Frontiers in Neurology, 2021
Multiple sclerosis is a neurodegenerative disease associated with demyelination and neuroinflammation in the central nervous system. There is an urgent need to develop remyelinating therapies to better treat multiple sclerosis and other demyelinating ...
Kelly F. Paton, Kelly F. Paton, Katharina Robichon, Katharina Robichon, Nikki Templeton, Nikki Templeton, Lisa Denny, Lisa Denny, Afnan Al Abadey, Afnan Al Abadey, Dan Luo, Thomas E. Prisinzano, Anne C. La Flamme, Anne C. La Flamme, Anne C. La Flamme, Bronwyn M. Kivell, Bronwyn M. Kivell   +16 more
doaj   +1 more source

Performance- and Resistance-Related Early Responses of Colombian Elite Rubber Tree Genotypes under Low Pressure of South American Leaf Blight: Implications for Disease Management in the Amazon

Plants, 2023
The cultivation of Hevea brasiliensis, the primary commercial source of natural rubber, is strongly impacted by South American leaf blight (SALB) disease, caused by the fungus Pseudocercospora ulei.
Lyda Constanza Galindo-Rodríguez, Armando Sterling, Herminton Muñoz-Ramirez, Jesica Andrea Fonseca-Restrepo   +3 more
doaj   +1 more source

Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress

Frontiers in Pharmacology, 2020
Background/Aims: Obesity-related kidney disease is associated with elevated levels of saturated free fatty acids (SFA). SFA lipotoxicity in tubular cells contributes to significant cellular apoptosis and injury.
Xiaoyi Mai, Xiaoyi Mai, Xin Yin, Peipei Chen, Peipei Chen, Minzhou Zhang, Minzhou Zhang   +6 more
doaj   +1 more source

Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1–Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway

Frontiers in Pharmacology, 2020
Acute kidney injury (AKI) is a serious disease characterized by a rapid decline in kidney function. Oxidative stress is the primary pathogenesis of AKI.
Yu Pang, Pei-chun Zhang, Rui-rui Lu, Hong-lian Li, Ji-cheng Li, Hong-xin Fu, Yi-Wen Cao, Guo-xing Fang, Bi-hao Liu, Bi-hao Liu, Jun-biao Wu, Jiu-yao Zhou, Yuan Zhou   +12 more
doaj   +1 more source

Evaluation of bacterial isolates of marine origin, such as biological control agents for Microcyclus ulei, the cause of the disease South American Rubber Sheets - (SALB) [PDF]

, 2023
ilustraciones, fotografías, gráficas, tablasEvaluación de aislamientos bacterianos de origen marino, como agentes de control biológico de Microcyclus ulei, causante del Mal Suramericano de las Hojas del Caucho - (SALB) La producción de látex del árbol de
Traslaviña Bernal, Cristian Alexander
core   +1 more source