A Novel Mechanism of Salvianolic Acid B in Postmyocardial Infarction Cardiac Protection: PHB1‐Driven Raf‐ERK Pathway Activation Promotes Cardiomyocyte Mitosis [PDF]
MedCommHeart failure (HF) following myocardial infarction remains a leading cause of global morbidity and mortality, necessitating novel therapeutic strategies. Salvianolic acid B (SalB), one of the major active components of Salvia miltiorrhiza Bunge, has been
Ce Cao +10 more
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Salvianolic acid B alleviates depression-like behaviors by reducing neuronal injury and promoting neurogenesis in a manner associated with JAK-STAT signaling pathway inhibition [PDF]
Frontiers in NeurologyBackgroundDepression is strongly associated with hippocampal neuroinflammation, neuronal damage and neurogenesis. Salvianolic acid B (SalB) has anti-inflammatory and neuroprotective potential, but whether its antidepressant effect is achieved by ...
Ni Wang +5 more
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Salvianolic Acid B Preserves Myocardial Viability and Extends the Preservation Window of Mouse Hearts During Static Cold Storage [PDF]
PharmaceuticalsBackground: Heart transplantation remains the definitive therapy for end-stage heart failure, but its success critically depends on optimal donor heart preservation.
Junyi Wang +3 more
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Salvianolic acid B: a promising cardioprotective agent [PDF]
Frontiers in ImmunologySalvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD).
Yingchun Shao +4 more
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Liposomal Salvianolic Acid B Enhances ALA-PDT in Oral Leucoplakia via ROS and AKT/mTOR Signalling [PDF]
International Dental Journal: Salvianolic acid B (SalB), a major component of Danshen, the ancient Chinese herb Salvia miltiorrhiza Bunge, has demonstrated inhibitory effects against various solid tumours.
Ying Zhang +6 more
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Association Between Serum Albumin and Periodontitis Across Disease Subgroups: A Cross-Sectional Study [PDF]
International Dental JournalPurpose: This study examines the association between serum albumin (sALB) levels and periodontitis severity, focusing on subgroup differences and nonlinear relationships.
Junwei Xiang +5 more
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Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases [PDF]
Frontiers in PharmacologyBackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory ...
Shijun Bi +6 more
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Defective Endothelial Glutaminolysis Contributes to Impaired Angiogenesis and Poor Ischemic Tissue Repair in Diabetes [PDF]
ResearchIt has been demonstrated that glutamine is a key player in boosting endothelial cell (EC) proliferation. However, despite its importance, the role of endothelial glutaminolysis in diabetes remains largely unexplored. Our research aimed to investigate the
Meina Zhao +11 more
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Risk assessment of pulmonary infections in primary glomerular diseases treated with rituximab [PDF]
Frontiers in ImmunologyPurposeThis study aimed to evaluate the incidence and risk factors of pulmonary infections in patients with primary glomerular diseases (PGDs) treated with rituximab (RTX).MethodsClinical data of patients treated with RTX were collected, along with ...
Chunyun Yang, Qiuyue Li
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Microenvironment-responsive nanoparticles functionalized titanium implants mediate redox balance and immunomodulation for enhanced osseointegration [PDF]
Materials Today BioVarious pathological conditions (e.g., diabetes, osteoporosis) are accompanied by persistent oxidative stress, which compromises the immune microenvironment and poses substantial challenges for osseointegration.
Wei Chen +8 more
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