Results 11 to 20 of about 7,535 (197)

Defective Endothelial Glutaminolysis Contributes to Impaired Angiogenesis and Poor Ischemic Tissue Repair in Diabetes [PDF]

Research
It has been demonstrated that glutamine is a key player in boosting endothelial cell (EC) proliferation. However, despite its importance, the role of endothelial glutaminolysis in diabetes remains largely unexplored. Our research aimed to investigate the
Meina Zhao, Jiaheng Zhou, Yang Hu, Xinpei Wang, Jiong An, Meijie Liu, Pengfei Zhang, Xing Zhang, Jingwen Wang, Xing Jin, Miaomiao Xi, Jia Li   +11 more
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Risk assessment of pulmonary infections in primary glomerular diseases treated with rituximab [PDF]

Frontiers in Immunology
PurposeThis study aimed to evaluate the incidence and risk factors of pulmonary infections in patients with primary glomerular diseases (PGDs) treated with rituximab (RTX).MethodsClinical data of patients treated with RTX were collected, along with ...
Chunyun Yang, Qiuyue Li
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The non-linear relationship between serum albumin and diabetic retinopathy in type 2 diabetes mellitus: a secondary analysis based on a cross-sectional study [PDF]

BMC Ophthalmology
Background Most studies had shown a linear relationship between serum albumin (sALB) and the prevalence of diabetic retinopathy (DR). Thus, the purpose of this study is to investigate whether their relationship is non-linear.
Guo-Qiang Zeng, Yu-Feng Yao, Jian-Bo Zhong, Yi Zhang, Bai-Kang Ye, Xiao-Yan Dou, Li Cai   +6 more
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Chitosan-salvianolic acid B coating on the surface of nickel-titanium alloy inhibits proliferation of smooth muscle cells and promote endothelialization [PDF]

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Intracranial stents are of paramount importance in managing cerebrovascular disorders. Nevertheless, the currently employed drug-eluting stents, although effective in decreasing in-stent restenosis, might impede the re-endothelialization ...
Shijun Bi, Shijun Bi, Hao Lin, Kunyuan Zhu, Kunyuan Zhu, Zechao Zhu, Wenxu Zhang, Xinyu Yang, Shanshan Chen, Jing Zhao, Meixia Liu, Pengyu Pan, Guobiao Liang   +12 more
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Microenvironment-responsive nanoparticles functionalized titanium implants mediate redox balance and immunomodulation for enhanced osseointegration [PDF]

Materials Today Bio
Various pathological conditions (e.g., diabetes, osteoporosis) are accompanied by persistent oxidative stress, which compromises the immune microenvironment and poses substantial challenges for osseointegration.
Wei Chen, Yifei Pan, Catherine Huihan Chu, Shuo Dong, Mingxi Wang, Long Wang, Lingxu Wang, Xuyang Lin, Chunbo Tang   +8 more
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Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage

Frontiers in Immunology, 2023
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a critical role in exacerbating early brain injury (EBI) after subarachnoid hemorrhage ...
Dayong Xia, Jinlong Yuan, Degang Wu, Haibin Dai, Zong Zhuang   +4 more
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Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway

Pharmaceutical Biology, 2022
Context Salvianolic acid B (SalB) can attenuate myocardial ischemia/reperfusion (I/R) injury, but the mechanisms are not entirely known.Objective Our study investigates if SalB protects cardiomyocytes against I/R injury by regulating Tripartite motif ...
Bo Lu, Jianhua Li, MingTai Gui, Lei Yao, Mingsong Fan, Xunjie Zhou, Deyu Fu   +6 more
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Early changes in serum albumin: impact on 2-year mortality in incident hemodialysis patients

Brazilian Journal of Nephrology, 2015
Introduction/objective: We evaluated the predictability of early changes in serum albumin (sAlb) on the two-year mortality of incident hemodialysis patients. Methods: Observational, longitudinal retrospective study using the database of Fresenius Medical
Giselly Rosa Modesto Pereira, Jorge Paulo Strogoff-de-Matos, Frederico Ruzany, Sergio Fernando Ferreira dos Santos, Eufrônio D'Almeida Filho, Marcos Sandro Fernandes de Vasconcelos, Ana Beatriz Barra, Jocemir Ronaldo Lugon   +7 more
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Performance- and Resistance-Related Early Responses of Colombian Elite Rubber Tree Genotypes under Low Pressure of South American Leaf Blight: Implications for Disease Management in the Amazon

Plants, 2023
The cultivation of Hevea brasiliensis, the primary commercial source of natural rubber, is strongly impacted by South American leaf blight (SALB) disease, caused by the fungus Pseudocercospora ulei.
Lyda Constanza Galindo-Rodríguez, Armando Sterling, Herminton Muñoz-Ramirez, Jesica Andrea Fonseca-Restrepo   +3 more
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Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways

Journal of Pharmacological Sciences, 2015
Acetaminophen (APAP) is used drugs worldwide for treating pain and fever. However, APAP overdose is the principal cause of acute liver failure in Western countries.
Musen Lin, Xiaohan Zhai, Guangzhi Wang, Xiaofeng Tian, Dongyan Gao, Lei Shi, Hang Wu, Qing Fan, Jinyong Peng, Kexin Liu, Jihong Yao   +10 more
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