Results 11 to 20 of about 1,480 (172)

Microenvironment-responsive nanoparticles functionalized titanium implants mediate redox balance and immunomodulation for enhanced osseointegration [PDF]

Materials Today Bio
Various pathological conditions (e.g., diabetes, osteoporosis) are accompanied by persistent oxidative stress, which compromises the immune microenvironment and poses substantial challenges for osseointegration.
Wei Chen, Yifei Pan, Catherine Huihan Chu, Shuo Dong, Mingxi Wang, Long Wang, Lingxu Wang, Xuyang Lin, Chunbo Tang   +8 more
doaj   +2 more sources

Structure and composition of supported lipid bilayers: a comparison between solvent-assisted lipid bilayer and vesicle fusion methods. [PDF]

J Appl Crystallogr
Neutron reflectometry is used to compare supported lipid bilayers formed by vesicle fusion and solvent‐assisted lipid bilayer (SALB) methods, revealing structurally comparable architectures with minor differences in acyl chain thickness and low residual solvent incorporation.
Felderer B, Buchanan C, Wang S, Shen HH, Nelson A, Hall SCL, Cárdenas M.   +6 more
europepmc   +2 more sources

An In Situ Embedded B-MOF Sponge With Shape-Memory for All-in-One Diabetic Wound Therapy. [PDF]

Adv Healthc Mater
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Zhou H, Huang C, Chen Y, Zhao T, Zhu F, Jun G, Zhang J, Pan Y, Wen Q, Yang L, Zhang H, Chen L.   +11 more
europepmc   +2 more sources

Salvianolic Acid B Alleviates MAFLD by Targeting PPAR-α: Mechanistic Insights From Network Pharmacology and Lipidomics. [PDF]

Food Sci Nutr
Salvianolic acid B (SALB) is the major water‐soluble bioactive constituent of Salvia miltiorrhiza Bunge, a traditional Asian health‐promoting food, while its therapeutic potential and molecular mechanisms in the pathogenesis of MAFLD remain largely unclear.
Huang F, Qiu C, Wang D, Ni Y, Fu Z, Fu L, Liang C, Huang S, Deng Z.   +8 more
europepmc   +2 more sources

Serum albumin levels and stress urinary incontinence in females: A retrospective study based on NHANES 2007–2016

Heliyon, 2023
Background: Serum albumin (sAlb) is an essential indicator of human physiological function. However, the correlation between the concentration of sAlb and stress urinary incontinence (SUI) remains poorly understood.
Mingming Xu, Hang Zhou, Yang Pan, Zhunan Xu, Xiaoqiang Liu   +4 more
doaj   +1 more source

Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage

Frontiers in Immunology, 2023
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a critical role in exacerbating early brain injury (EBI) after subarachnoid hemorrhage ...
Dayong Xia, Jinlong Yuan, Degang Wu, Haibin Dai, Zong Zhuang   +4 more
doaj   +1 more source

Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway

Pharmaceutical Biology, 2022
Context Salvianolic acid B (SalB) can attenuate myocardial ischemia/reperfusion (I/R) injury, but the mechanisms are not entirely known.Objective Our study investigates if SalB protects cardiomyocytes against I/R injury by regulating Tripartite motif ...
Bo Lu, Jianhua Li, MingTai Gui, Lei Yao, Mingsong Fan, Xunjie Zhou, Deyu Fu   +6 more
doaj   +1 more source

Early changes in serum albumin: impact on 2-year mortality in incident hemodialysis patients

Brazilian Journal of Nephrology, 2015
Introduction/objective: We evaluated the predictability of early changes in serum albumin (sAlb) on the two-year mortality of incident hemodialysis patients. Methods: Observational, longitudinal retrospective study using the database of Fresenius Medical
Giselly Rosa Modesto Pereira, Jorge Paulo Strogoff-de-Matos, Frederico Ruzany, Sergio Fernando Ferreira dos Santos, Eufrônio D'Almeida Filho, Marcos Sandro Fernandes de Vasconcelos, Ana Beatriz Barra, Jocemir Ronaldo Lugon   +7 more
doaj   +1 more source

Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways

Journal of Pharmacological Sciences, 2015
Acetaminophen (APAP) is used drugs worldwide for treating pain and fever. However, APAP overdose is the principal cause of acute liver failure in Western countries.
Musen Lin, Xiaohan Zhai, Guangzhi Wang, Xiaofeng Tian, Dongyan Gao, Lei Shi, Hang Wu, Qing Fan, Jinyong Peng, Kexin Liu, Jihong Yao   +10 more
doaj   +1 more source

The Salvinorin Analogue, Ethoxymethyl Ether Salvinorin B, Promotes Remyelination in Preclinical Models of Multiple Sclerosis

Frontiers in Neurology, 2021
Multiple sclerosis is a neurodegenerative disease associated with demyelination and neuroinflammation in the central nervous system. There is an urgent need to develop remyelinating therapies to better treat multiple sclerosis and other demyelinating ...
Kelly F. Paton, Kelly F. Paton, Katharina Robichon, Katharina Robichon, Nikki Templeton, Nikki Templeton, Lisa Denny, Lisa Denny, Afnan Al Abadey, Afnan Al Abadey, Dan Luo, Thomas E. Prisinzano, Anne C. La Flamme, Anne C. La Flamme, Anne C. La Flamme, Bronwyn M. Kivell, Bronwyn M. Kivell   +16 more
doaj   +1 more source