Salvianolic acid B: a promising cardioprotective agent [PDF]
Frontiers in ImmunologySalvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD).
Yingchun Shao +4 more
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Salvianolic acid B alleviates depression-like behaviors by reducing neuronal injury and promoting neurogenesis in a manner associated with JAK-STAT signaling pathway inhibition [PDF]
Frontiers in NeurologyBackgroundDepression is strongly associated with hippocampal neuroinflammation, neuronal damage and neurogenesis. Salvianolic acid B (SalB) has anti-inflammatory and neuroprotective potential, but whether its antidepressant effect is achieved by ...
Ni Wang +5 more
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Association Between Serum Albumin and Periodontitis Across Disease Subgroups: A Cross-Sectional Study [PDF]
International Dental JournalPurpose: This study examines the association between serum albumin (sALB) levels and periodontitis severity, focusing on subgroup differences and nonlinear relationships.
Junwei Xiang +5 more
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Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases [PDF]
Frontiers in PharmacologyBackgroundNeurological diseases such as stroke and Alzheimer’s disease pose increasing challenges to global public health. Salvianolic Acid B (SalB), a major active component of Salvia miltiorrhiza, has garnered attention due to its anti-inflammatory ...
Shijun Bi +6 more
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Liposomal Salvianolic Acid B Enhances ALA-PDT in Oral Leucoplakia via ROS and AKT/mTOR Signalling [PDF]
International Dental Journal: Salvianolic acid B (SalB), a major component of Danshen, the ancient Chinese herb Salvia miltiorrhiza Bunge, has demonstrated inhibitory effects against various solid tumours.
Ying Zhang +6 more
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Defective Endothelial Glutaminolysis Contributes to Impaired Angiogenesis and Poor Ischemic Tissue Repair in Diabetes [PDF]
ResearchIt has been demonstrated that glutamine is a key player in boosting endothelial cell (EC) proliferation. However, despite its importance, the role of endothelial glutaminolysis in diabetes remains largely unexplored. Our research aimed to investigate the
Meina Zhao +11 more
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Salvianolic acid B in fibrosis treatment: a comprehensive review [PDF]
Frontiers in PharmacologyFibrosis is a public health issue of great concern characterized by the excessive deposition of extracellular matrix, leading to the destruction of parenchymal tissue and organ dysfunction that places a heavy burden on the global healthcare system due to
Qingzhi Liang +15 more
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Risk assessment of pulmonary infections in primary glomerular diseases treated with rituximab [PDF]
Frontiers in ImmunologyPurposeThis study aimed to evaluate the incidence and risk factors of pulmonary infections in patients with primary glomerular diseases (PGDs) treated with rituximab (RTX).MethodsClinical data of patients treated with RTX were collected, along with ...
Chunyun Yang, Qiuyue Li
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The non-linear relationship between serum albumin and diabetic retinopathy in type 2 diabetes mellitus: a secondary analysis based on a cross-sectional study [PDF]
BMC OphthalmologyBackground Most studies had shown a linear relationship between serum albumin (sALB) and the prevalence of diabetic retinopathy (DR). Thus, the purpose of this study is to investigate whether their relationship is non-linear.
Guo-Qiang Zeng +6 more
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Microenvironment-responsive nanoparticles functionalized titanium implants mediate redox balance and immunomodulation for enhanced osseointegration [PDF]
Materials Today BioVarious pathological conditions (e.g., diabetes, osteoporosis) are accompanied by persistent oxidative stress, which compromises the immune microenvironment and poses substantial challenges for osseointegration.
Wei Chen +8 more
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