Results 11 to 20 of about 2,338 (206)

Early changes in serum albumin: impact on 2-year mortality in incident hemodialysis patients

open access: yesBrazilian Journal of Nephrology, 2015
Introduction/objective: We evaluated the predictability of early changes in serum albumin (sAlb) on the two-year mortality of incident hemodialysis patients. Methods: Observational, longitudinal retrospective study using the database of Fresenius Medical
Giselly Rosa Modesto Pereira   +7 more
doaj   +2 more sources

Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways [PDF]

open access: yesJournal of Pharmacological Sciences, 2015
Acetaminophen (APAP) is used drugs worldwide for treating pain and fever. However, APAP overdose is the principal cause of acute liver failure in Western countries.
Musen Lin   +10 more
doaj   +2 more sources

A Cocktail Method for Promoting Cardiomyocyte Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells [PDF]

open access: yesStem Cells International, 2014
A growing body of evidence supports the argument that bone marrow-derived mesenchymal stem cells (MSCs) can differentiate into cardiomyocyte-like cells in an appropriate cellular environment, but the differentiation rate is low.
Qing Gao   +5 more
doaj   +2 more sources

Salvianolic Acid B Ameliorates Lipopolysaccharide-Induced Albumin Leakage from Rat Mesenteric Venules through Src-Regulated Transcelluar Pathway and Paracellular Pathway.

open access: yesPLoS ONE, 2015
Lipopolysaccharide (LPS) causes microvascular barrier disruption, leading to albumin leakage from microvessels resulting in a range of disastrous sequels.
Chun-Shui Pan   +12 more
doaj   +2 more sources

Salvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease models.

open access: yesPLoS ONE, 2014
Salvianolic acid B (SalB), a bioactive compound isolated from the plant-derived medicinal herb Danshen, has been shown to exert various anti-oxidative and anti-inflammatory activities in several neurological disorders.
Jie Zhou   +6 more
doaj   +2 more sources

Combined Salvianolic Acid B and Ginsenoside Rg1 Exerts Cardioprotection against Ischemia/Reperfusion Injury in Rats.

open access: yesPLoS ONE, 2015
Lack of pharmacological strategies in clinics restricts the patient prognosis with myocardial ischemia/reperfusion (I/R) injury. The aim of this study was to evaluate the cardioprotection of combined salvianolic acid B (SalB) and ginsenoside Rg1 (Rg1 ...
Yanping Deng   +16 more
doaj   +2 more sources

Cardio-protection of salvianolic acid B through inhibition of apoptosis network.

open access: yesPLoS ONE, 2011
Targeting cellular function as a system rather than on the level of the single target significantly increases therapeutic potency. In the present study, we detect the target pathway of salvianolic acid B (SalB) in vivo.
Lingling Xu   +13 more
doaj   +2 more sources

The non-linear relationship between serum albumin and diabetic retinopathy in type 2 diabetes mellitus: a secondary analysis based on a cross-sectional study

open access: yesBMC Ophthalmology
Background Most studies had shown a linear relationship between serum albumin (sALB) and the prevalence of diabetic retinopathy (DR). Thus, the purpose of this study is to investigate whether their relationship is non-linear.
Guo-Qiang Zeng   +6 more
doaj   +2 more sources

Affinity-Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics. [PDF]

open access: yesAdv Healthc Mater
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
He X   +9 more
europepmc   +2 more sources

Serum albumin levels and stress urinary incontinence in females: A retrospective study based on NHANES 2007–2016

open access: yesHeliyon, 2023
Background: Serum albumin (sAlb) is an essential indicator of human physiological function. However, the correlation between the concentration of sAlb and stress urinary incontinence (SUI) remains poorly understood.
Mingming Xu   +4 more
doaj   +1 more source

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