Results 41 to 50 of about 64,328 (314)

Anticholinergic therapy for acute asthma in children. [PDF]

, 2012
Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in ...
Beakes, Beck, Benito Fernandez, Bever, Bratteby, British Thoracic Society, Brown, Browne, Calvo, Cook, Craven, Cugell, DeStefano, Ducharme, Everard, Goggin, Gross, Guill, Hayday, Iramain, Lew, Lin, Lung, Mallol, McDonald, Mirsadraee, National Asthma Council Australia, Ni, Plotnick, Pulejo, Quereshi, Qureshi, Rayner, Reisman, Rodrigo, Schuh, Sienra Monge, Storms, Storr, Tal, Timsit, Ulrik, Undem, Wade, Ward, Ward, Yeung, Youngchaiyud, Zimmerman, Zorc   +49 more
core   +2 more sources

Effect of single doses of S-salbutamol, R-salbutamol, racemic salbutamol, and placebo on the airway response to methacholine. [PDF]

Thorax, 1997
Commercially available salbutamol is a racemic mixture consisting of equal amounts of the two enantiomers, R-salbutamol and S-salbutamol, felt to be active and inert, respectively.A double blind, randomised, four way, crossover study was performed in 12 well controlled asthmatic subjects (forced expiratory volume in one second (FEV1) > 70% predicted ...
Donald W. Cockcroft, V A Swystun
openaire   +3 more sources

Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus

Clinical Pharmacokinetics, 2019
Background Intravenous salbutamol is used to treat children with refractory status asthmaticus, however insufficient pharmacokinetic data are available to guide initial and subsequent dosing recommendations for its intravenous use.
N. Vet, B. D. de Winter, M. Koninckx, S. Boeschoten, A. Boehmer, Jacintha T C M Verhallen, F. Plötz, A. Vaessen-Verberne, Bart C. H. van der Nagel, C. Knibbe, C. Buysse, S. D. de Wildt, B. Koch, M. de Hoog   +13 more
semanticscholar   +1 more source

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]

, 2018
BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E, Corsello, G, Indinnimeo, L, Miraglia del Giudice, M   +3 more
core   +1 more source

Nebulized heparin and salbutamol versus salbutamol alone in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation: a double-blind randomized controlled trial [PDF]

Korean Journal of Anesthesiology, 2020
Background Nebulized heparin has been effectively used in the management of many pulmonary diseases. However, its effect on mechanically ventilated patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD) has never been studied ...
Tarek Mohamed Ashoor, Ahmad Mahmoud Hasseb, Ibrahim Mamdouh Esmat   +2 more
doaj   +1 more source

Longitudinal evaluation of SMN levels as biomarker for spinal muscular atrophy: results of a phase IIb double-blind study of salbutamol

Journal of Medical Genetics, 2018
Background Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder, due to the loss of function of the survival motor neuron (SMN1) gene. The first treatment for the condition, recently approved, is based on the reduction of exon 7
F. Tiziano, R. Lomastro, E. Abiusi, M. Pasanisi, Lorena Di Pietro, S. Fiori, G. Baranello, C. Angelini, G. Soraru', A. Gaiani, T. Mongini, L. Vercelli, E. Mercuri, G. Vasco, M. Pane, G. Vita, G. Vita, S. Messina, R. Petillo, L. Passamano, L. Politano, A. Campanella, R. Mantegazza, L. Morandi   +23 more
semanticscholar   +1 more source

Onset of bronchodilation with fluticasone/formoterol combination versus fluticasone/salmeterol in an open-label, randomized study [PDF]

, 2012
Introduction: The inhaled corticosteroid, fluticasone propionate (fluticasone), and the long-acting beta2-agonist, formoterol fumarate (formoterol), have been combined in a single aerosol inhaler (fluticasone/formoterol).
Aalbers, René, Bodzenta-Lukaszyk, Anna, Brusselle, Guy, Grothe, Birgit, McIver, Tammy   +4 more
core   +1 more source

Spatial Distribution of (R)-salbutamol in Rat Brain Following Nasal and Intravenous Administration Using DESI-MS

Pharmaceutics, 2020
Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s
Rui Zhang, Jie Wu, Siyu Liu, LiangJun Deng, Junhua Hu, Xi Chen, Wen Tan   +6 more
doaj   +1 more source

The topical study of inhaled drug (salbutamol) delivery in idiopathic pulmonary fibrosis

Respiratory Research, 2018
BackgroundOur aim was to investigate total and regional lung delivery of salbutamol in subjects with idiopathic pulmonary fibrosis (IPF).MethodsThe TOPICAL study was a 4-period, partially-randomised, controlled, crossover study to investigate four ...
O. Usmani, M. Biddiscombe, Shuying Yang, S. Meah, E. Oballa, J. Simpson, W. Fahy, R. Marshall, P. Lukey, T. Maher   +9 more
semanticscholar   +1 more source

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events [PDF]

, 2012
An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in previous Cochrane reviews.ObjectivesWe set out to compare the risks of mortality and non-fatal serious adverse events in ...
Altman, Blauw, Cates, Cates, Cates, Cates, Cates, Ducharme, Giembycz, Greenstone, Lipworth, Nelson, Ni Chroinin, Ni Chroinin, Pearce, Salpeter, Sears, Walters, Walters   +18 more
core   +1 more source