Results 91 to 100 of about 7,877 (239)

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica [PDF]

, 2017
Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on ...
A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Saccani, A Schmieder, A Sica, A Sica, B Ruffell, B Shao, BB Aggarwal, BC Kennedy, BK Sekhon, C Jia, C Liu, C Steidl, CE Lewis, CK Mueller, Curzio Rüegg, D Ghosh, DM Mosser, E Bolli, E Schutyser, F Li, F Zhao, FO Martinez, FR Zhao, G Shu, G Solinas, H Diao, H Fritz, H Kurahara, H Kurahara, H Ouyang, H Wang, H Wang, H Zhang, H Zhao, HYT Nguyen, IA Schepetkin, J Cook, J Deng, J Ding, J Gao, J Li, J Li, J Li, J Rius, J Wang, J Yin, J Zhang, JB Mitchem, JW Pollard, JY Jang, JY Shin, Kun Zhou, L Bingle, L Sanchez-Martin, L Varinska, LI Partecke, Li-kang Sun, Lin Miao, M Egeblad, M Hong, M Ito, M Jinushi, M Pesic, MA Khan, Margaret Gebauer, Micheal O. Hottiger, ML Taddei, MR Galdiero, Muriel Cuendet, MY Kim, P Allavena, P Suboj, P Sun, P Yu, PS Kyrn, Q Dong, Q Lin, R Graziose, R Noy, R Ostuni, R Zhu, S Banerjee, S Gao, S Iwanowycz, S Lunardi, S Shi, S Shimura, S Ye, SM Woo, SR Hingorani, SR Hyam, T Kawanishi, T Xu, V Riabov, W Lam, W Shi, Wei-ling Pu, X Jia, X Li, X Lin, X Nie, X Qian, X Sun, X Tang, X Wang, X Zhan, X Zhang, X Zhang, Xiu-mei Gao, XL Zhu, XW Yang, Y Cai, Y Kimura, Y Lei, Y Liu, Y Song, Y Tu, Y Wang, Y Wang, Y Zhao, YP Guo, Yun-sha Zhang, Z Cai, Z Jiang, Z Lin, Z Liu   +131 more
core   +1 more source

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, Volume 103, Issue 8, Page 998-1009, December 2025.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Exploring Artificial Intelligence's Potential to Enhance Conventional Anticancer Drug Development

Drug Development Research, Volume 86, Issue 7, November 2025.
ABSTRACT Cancer affects one in three to four people globally, with over 20 million new cases and 10 million deaths annually, projected to rise to 35 million cases by 2050. Developing effective cancer treatments is crucial, but the drug discovery process is a highly complex and expensive endeavor, with success rates sitting well below 10% for oncologic ...
Sorin‐Ștefan Bobolea, Miruna‐Ioana Hinoveanu, Andreea Dimitriu, Miruna‐Andrada Brașoveanu, Cristian‐Nicolae Iliescu, Cristina‐Elena Dinu‐Pîrvu, Mihaela Violeta Ghica, Valentina Anuța, Lăcrămioara Popa, Răzvan Mihai Prisada   +9 more
wiley   +1 more source

RETRACTED: Salidroside alleviates cigarette smoke-induced COPD in mice

Biomedicine & Pharmacotherapy, 2017
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the authors, who have informed the Editor-in-Chief that they had not obtained the necessary ethical approval for the animal studies before performing the experiments.
Fen, Luo, Jingyan, Liu, Tianhua, Yan, Mingxing, Miao   +3 more
openaire   +2 more sources

Production of three phenylethanoids, tyrosol, hydroxytyrosol, and salidroside, using plant genes expressing in Escherichia coli

Scientific Reports, 2017
Polyphenols, which include phenolic acids, flavonoids, stilbenes, and phenylethanoids, are generally known as useful antioxidants. Tyrosol, hydroxytyrosol, and salidroside are typical phenylethanoids.
Daeun Chung, So Yeon Kim, Joong-Hoon Ahn
doaj   +1 more source

Simultaneous Preparation of Salidroside and p-Tyrosol from Rhodiola crenulata by DIAION HP-20 Macroporous Resin Chromatography Combined with Silica Gel Chromatography

Molecules, 2018
The Rhodiola species have a long history of utilization in traditional medicine and have been considered as a source of adaptation to environmental challenges; salidroside and p-tyrosol are the major responsible compounds.
Liwei Sun, Ran Zhou, Jinling Sui, Yujun Liu   +3 more
doaj   +1 more source

Protection by salidroside against bone loss via inhibition of oxidative stress and bone-resorbing mediators. [PDF]

PLoS ONE, 2013
Oxidative stress is a pivotal pathogenic factor for bone loss in mouse model. Salidroside, a phenylpropanoid glycoside extracted from Rhodiola rosea L, exhibits potent antioxidative effects.
Jin-Kang Zhang, Liu Yang, Guo-Lin Meng, Zhi Yuan, Jing Fan, Dan Li, Jian-Zong Chen, Tian-Yao Shi, Hui-Min Hu, Bo-Yuan Wei, Zhuo-Jing Luo, Jian Liu   +11 more
doaj   +1 more source

Salidroside pretreatment protects against myocardial injury induced by heat stroke in mice

Journal of International Medical Research, 2019
Objective To explore the protective effects and mechanisms of salidroside on myocardial injury induced by heat stroke (HS) in mice. Methods We pretreated mice with salidroside for 1 week and then established an HS model by exposure to 41.2°C for 1 hour ...
Guo-dong Chen, Heng Fan, Jian-Hua Zhu
doaj   +1 more source

The Role of Extracellular Vesicles in Musculoskeletal Diseases

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT Extracellular Vesicles (EVs), nanoscale membrane‐bound cell‐released structures, are vital for intercellular communication and material transport. Their role in musculoskeletal health and diseases has recently drawn significant attention.
Peng‐jie Fu, Yan Luo, Sheng‐yuan Zheng, Zhe‐ru Ma, Wen‐feng Xiao, Hui Li, Yu‐sheng Li   +6 more
wiley   +1 more source

Salidroside Attenuates Allergic Airway Inflammation Through Negative Regulation of Nuclear Factor-Kappa B and p38 Mitogen–Activated Protein Kinase

Journal of Pharmacological Sciences, 2014
.: Salidroside is a biologically active ingredient of Rhodiola rosea, which has several interesting biological properties, including anti-oxidant and anti-inflammatory; however, its anti-allergic effects are poorly understood. The objective of this study
Guang Hai Yan, Yun Ho Choi
doaj   +1 more source