Results 11 to 20 of about 7,877 (239)

The metabolism of salidroside to its aglycone p-tyrosol in rats following the administration of salidroside. [PDF]

PLoS ONE, 2014
Salidroside is one of the major phenolic glycosides in Rhodiola, which has been reported to possess various biological activities. In the present study the in vivo deglycosylation metabolism of salidroside was investigated and its aglycone p-tyrosol but ...
Na Guo, Meixuan Zhu, Xuejiao Han, Dan Sui, Yang Wang, Qian Yang   +5 more
doaj   +4 more sources

Antiatherosclerotic Effect and Molecular Mechanism of Salidroside

Reviews in Cardiovascular Medicine, 2023
Atherosclerotic cardiovascular disease is currently the leading cause of death worldwide. Its pathophysiological basis includes endothelial dysfunction, macrophage activation, vascular smooth muscle cell (VSMC) proliferation, lipid metabolism, platelet ...
Si-Fan Fei, De-Bing Tong, Fang Jia
doaj   +3 more sources

Salidroside: A Promising Agent in Bone Metabolism Modulation

Nutrients
Rhodiola rosea, a long-lived herbaceous plant from the Crassulaceae group, contains the active compound salidroside, recognized as an adaptogen with significant therapeutic potential for bone metabolism.
Piotr Wojdasiewicz, Stanisław Brodacki, Ewa Cieślicka, Paweł Turczyn, Łukasz A Poniatowski, Weronika Ławniczak, M. Olczak, E. Stolarczyk, Edyta Wróbel, Agnieszka Mikulska, Anna Lach-Gruba, Beata Żuk, Katarzyna Romanowska-Próchnicka, D. Szukiewicz   +13 more
semanticscholar   +3 more sources

Effects of salidroside on atherosclerosis: potential contribution of gut microbiota

Frontiers in Pharmacology
Much research describes gut microbiota in atherosclerotic cardiovascular diseases (ASCVD) for that the composition of the intestinal microbiome or its metabolites can directly participate in the development of endothelial dysfunction, atherosclerosis and
Si-Fan Fei, Can Hou, Fang Jia
doaj   +2 more sources

Salidroside ameliorates acute liver transplantation rejection in rats by inhibiting neutrophil extracellular trap formation

Acta Biochimica et Biophysica Sinica
Acute rejection is an important factor affecting the survival of recipients after liver transplantation. Salidroside has various properties, including anti-inflammatory, antioxidant, and hepatoprotective properties. This study aims to investigate whether
Qin Xiaoyan, Wang Han, Li Qi, Hu Dingheng, Wang Liangxu, Zhou Baoyong, Liao Rui, Liu Yanyao   +7 more
doaj   +2 more sources

The effect of salidroside in promoting endogenous neural regeneration after cerebral ischemia/reperfusion involves notch signaling pathway and neurotrophic factors

BMC Complementary Medicine and Therapies
Background Salidroside is the major bioactive and pharmacological active substance in Rhodiola rosea L. It has been reported to have neuroprotective effects on cerebral ischemia/reperfusion (I/R).
Jiabing Zheng, Jizhou Zhang, Jing Han, Zhichang Zhao, Kan Lin   +4 more
doaj   +2 more sources

Salidroside ameliorates neuroinflammation in autistic rats by inhibiting NLRP3/Caspase-1/GSDMD signal pathway

Brain Research Bulletin
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that place a huge economic and emotional burden on society. Salidroside (Sal) has been reported to have therapeutic effects in a variety of neurological disorders such as ...
Qingwei Wu, Xiaohang Shan, Xuemei Li, Jian Guan, Fanxu Song, Xinyu Zhou, Yingying Fan, Lanmin Guo   +7 more
doaj   +2 more sources

Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway

Journal of Orthopaedic Surgery and Research
Background Bone loss caused by microgravity exposure presents a serious threat to the health of astronauts, but existing treatment strategies have specific restrictions.
Nan Wang, Zhuan Zuo, Tong Meng, Yuliang Liu, Xiwei Zheng, Yongsheng Ma   +5 more
doaj   +2 more sources

Antihypothyroid Effect of Salidroside

Molecules, 2022
In terms of prevalence, thyroid pathology, associated both with a violation of the gland function and changes in its structure, occupies one of the main places in clinical endocrinology. The problem of developing low-toxic and highly effective herbal preparations for the correction of thyroid hypofunction and its complications is urgent. Salidroside is
Nazym K. Korbozova, Nataliya O. Kudrina, Nataliya A. Zhukova, Alexander E. Grazhdannikov, Irina V. Blavachinskaya, Gulnaz A. Seitimova, Timur E. Kulmanov, Tatyana G. Tolstikova, Nina V. Terletskaya   +8 more
openaire   +3 more sources

Salidroside attenuates oxygen and glucose deprivation-induced neuronal injury by inhibiting ferroptosis

Asian Pacific Journal of Tropical Biomedicine, 2023
Objective: To evaluate the effect of salidroside on oxygen and glucose deprivation (OGD)-treated NT2 cells and its underlying mechanisms of action. Methods: Retinoic acid was used to induce the differentiation of NT2 cells into neurons.
Ying-Zhi Li, Ai-Ping Wu, Dan-Dan Wang, Pan-Pan Yang, Bin Sheng   +4 more
doaj   +1 more source