Results 201 to 210 of about 7,877 (239)

Advances in Research on Anticancer Properties of Salidroside

Chinese Journal of Integrative Medicine, 2020
Salidroside is a phenolic secondary metabolite present in plants of the genus Rhodiola, and studies investigating its extensive pharmacological activities and mechanisms have recently attracted increasing attention. This review summarizes the progress of recent research on the antiproliferative activities of salidroside and its effects on breast ...
An-Qi, Sun, Xiu-Lian, Ju
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Synthesis, Purification, and Activity of Salidroside

Journal of Liquid Chromatography & Related Technologies, 2007
Abstract Our goal was to synthesise this compound by glucosylation of p‐tyrosol. The 74% yield of the reaction was not satisfactory and instead of optimising the procedure, we preferred to purify the product. This was achieved by high performance centrifugal partition chromatography with an optimised biphasic system followed by a solid phase extraction
Delépée, Raphaël, Berteina-Rabouin, S., Lafosse, Michel, Lamy, Cécile, Darnault, Sylvie, Renimel, Isabelle, About, Nancy, André, Patrice   +7 more
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Salidroside promotes healthy longevity by interfering with HSP90 activity

GeroScience, 2023
Aging is a risk factor for human health and quality of life. Screening and development of novel supplements and medications to combat aging and delay the incidence of age-related diseases are of great significance. In this study, salidroside (SA), a primary natural small molecule from Rhodiola rosea, was investigated regarding its effects on life and ...
Jianfei Zhang, Zhiquan Li, Jiangbo Song, Lei Zhou, Xin Chen, Wen Ge, Tianyi Dong, Yuxin Luo, Ting Mao, Zheng Li, Duan Tan, Lene Juel Rasmussen, Vilhelm A. Bohr, Xiaoling Tong, Fangyin Dai   +14 more
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A Salidroside‐Based Radiosensitizer Regulates the Nrf2/ROS Pathway for X‐Ray Activated Synergistic Cancer Precise Therapy

Advances in Materials
The hypoxic microenvironment and radioresistance of tumor cells, as well as the delay in efficacy evaluation, significantly limit the effect of clinical radiotherapy.
Qingqing Li, Qing Chen, Shenggan Xiao, Shuhan Wang, Xiaoguang Ge, Qian Wang, Liting Zheng, Qiaoqiao Wei, Wei Du, Wenbin Shen, Ying Wu, Jibin Song   +11 more
semanticscholar   +1 more source

Salidroside Attenuates Liver Injury in Diabetes Mice

SSRN Electronic Journal, 2020
Background and Purpose: High mobility group box 1 (HMGB1) is a nuclear protein that is released on injury triggers inflammation. This study aims to elucidate the effects of salidroside on diabetes-induced liver inflammation. Experimental Approach: The levels of glucose, inflammatory cytokines and hepatic functional parameters in serum and liver of ...
Limin Yang, Lin Zhou, Wang Wang, Xiaohui Wang, Jin Wang   +4 more
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Endoplasmic Reticulum Stress and NF-κB Pathway in Salidroside Mediated Neuroprotection: Potential of Salidroside in Neurodegenerative Diseases

The American Journal of Chinese Medicine, 2017
Microglial activation leads to increased production of proinflammatory enzymes and cytokines, which is considered to play crucial role in neurodegenerative diseases, however there are only a few drugs that target microglia activation. Recent studies have indicated that the Traditional Chinese Medicine, salidroside (Sal), exerted anti-inflammatory ...
Chenggui Wang, Yiting Lou, Jianxiang Xu, Zhenhua Feng, Yu Chen, Qian Tang, Qingqing Wang, Haiming Jin, Yaosen Wu, Naifeng Tian, Yifei Zhou, Huazi Xu, Xiaolei Zhang   +12 more
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Effect of Salidroside on Cardiac Functional Recovery

Advanced Materials Research, 2013
To investigate the cardioprotective effect of salidroside to rat heart subjected to 8-hour hypothermic storage and 2-hour normothermic reperfusion. Isolated rat hearts were perfused with Langendorff model; after 30 minutes of baseline, the hearts were arrested and stored by St.
Yan Zhang, Zhong Hua Zheng, Yue Peng Wang, Guo Liang Peng, Liu Hang Wang   +4 more
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Ginsenosides, salidroside, and syringin complex exhibits anti-fatigue in exhaustive exercise rats

International Journal of Medical Sciences
Excessive exercise can lead to fatigue, consequently affect exercise performance, and further have an adverse impact to human health. The synergistic effects of ginsenosides, salidroside, and syringin on improving exercise performance remain unknown ...
Yung-Chun Wu, Yu Zhi Lian, Hongwei Zhao, Lei Wang, Deshan Ning, J. Chao   +5 more
semanticscholar   +1 more source

Salidroside attenuates cardiac dysfunction in a rat model of diabetes

Diabetic Medicine, 2021
AbstractAimThis study aimed to investigate the therapeutic effects of salidroside on diabetes‐induced cardiovascular disease.MethodsSprague–Dawley rats treated with 65 mg/kg of streptozotocin (STZ) on a daily basis were used to establish the diabetic rat model (blood glucose levels >13.9 mmol/L).
Weiwei Hao, Na Li, Caifeng Mi, Qiang Wang, Yuanyuan Yu   +4 more
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Salidroside - Can it be a Multifunctional Drug?

Current Drug Metabolism, 2020
Background:Salidroside is a glucoside of tyrosol found mostly in the roots of Rhodiola spp. It exhibits diverse biological and pharmacological properties. In the last decade, enormous research is conducted to explore the medicinal properties of salidroside; this research reported many activities like anti-cancer, anti-oxidant, anti-aging, anti-diabetic,
Sri Krishna Jayadev Magani, Sri Durgambica Mupparthi, Bhanu Prakash Gollapalli, Dhananjay Shukla, AK Tiwari, Jyotsna Gorantala, Nagendra Sastry Yarla, Srinivasan Tantravahi   +7 more
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