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Cerebral effects of isovolemic hemodilution with a hypertonic saline solution
Journal of Neurosurgery, 1985✓ In view of a growing interest in the resuscitative use of hypertonic saline solutions, the authors have examined the cerebral effects of isovolemic hemodilution carried out over 1 hour (hematocrit decreased from 40% to 20%, stable arterial and right arterial pressures), using a hypertonic lactated Ringer's solution (HT-LR:Na+ 252 mEq/liter ...
M M, Todd, C, Tommasino, S, Moore
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Hypertonic saline solutions for treatment of intracranial hypertension
Current Opinion in Anaesthesiology, 2007This review aims to provide an update on recent knowledge gained on hypertonic saline solutions for the treatment of intracranial hypertension. Explanatory approaches to the mechanisms underlying the edema-reducing effects of the solutions are outlined, practical aspects of use are presented, and trials that assessed their clinical utility are ...
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Influence of Hypertonic Saline Solution Infusion on Defibrillation Efficacy
Chest, 1996Hypertonic saline solution may enhance cardiac conduction via the fast inward sodium channel and alter transmembrane Ca+2 conductance via the sodium-calcium exchanger. Evidence suggests that both Ca+2 conductance and myocardial conduction velocity may affect ventricular defibrillation. Since hypertonic saline solution solutions (ie, sodium bicarbonate)
M R, Ujhelyi +6 more
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Dose Response Characteristics of Hypertonic Saline Dextran Solutions
The Journal of Trauma: Injury, Infection, and Critical Care, 1991In an effort to find the best hypertonic saline-dextran solution (HSD) for prehospital use, 33 chronically catheterized sheep were bled using a fixed pressure shock model (50 mm Hg x 2 hours) and resuscitated with 4 ml/kg of HSD solution (2-minute bolus).
L, Halvorsen +3 more
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Small-Volume Resuscitation with Hypertonic Saline Dextran Solution
Survey of Anesthesiology, 1987Small-volume hypertonic resuscitation has been proposed as an effective means for restoration of cardiovascular function after hemorrhage at the scene of an accident. We evaluated the cardiovascular, metabolic, and neurohumoral response of resuscitation after hemorrhage using 200 ml of 2400 mosm sodium chloride, 6% dextran 70.
G C, Kramer +6 more
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Hypertonic saline-dextran solutions for the prehospital management of traumatic hypotension
The American Journal of Surgery, 1989We report the results of the first clinical study on the use of a hypertonic saline-dextran solution for the prehospital management of hypotensive victims of penetrating trauma. During a 4-month period, 48 trauma patients with penetrating injuries and a prehospital systolic blood pressure of 90 mm Hg or less were infused in-field with 250 ml of either ...
P A, Maningas +5 more
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[Hemodynamic effects of hypertonic saline solutions].
Annales francaises d'anesthesie et de reanimation, 1998Haemodynamic effects of hypertonic saline solutions (HSS) have been extensively studied in animals and humans. Hypertonic sodium chloride (7.5%, 2,500 mOsm.L-1) either alone or combined with colloids, remains the standard solution. The haemodynamic response of HSS observed during treatment of hypovolaemic shock is explained by 1) an increase in preload
F, Sztark, J P, Gékière, P, Dabadie
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Physiologic and hypertonic saline solutions impair ciliary activity in vitro
The Laryngoscope, 1999AbstractObjective/Hypothesis: Physiologic saline (NaCl 0.9%) is commonly used in treating acute and chronic rhinosinusitis. Moreover, physiologic saline is used as a control medium, vehicle, or solvent in studies on ciliary beat frequency (CBF). Hypertonic saline (NaCl 7% and 14.4%) has been applied in attempts to enhance mucociliary transport in ...
Boek, W.M. +3 more
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Hypertonic saline solutions in shock resuscitation.
Compendium (Yardley, PA), 2013Hypertonic saline solutions (HSS) have several characteristics that may improve the survival of patients during the initial treatment of certain types of shock. The use of isotonic crystalloids for resuscitation has several limitations: large infusion volumes are needed to increase the intravascular space; these large volumes cannot be given rapidly ...
Jennifer, Kyes, Justine A, Johnson
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Inadvertent Subcutaneous Injection of Hypertonic Saline Solution During Lipofilling
Aesthetic Plastic Surgery, 2013Subcutaneous infiltration with a mixture of plain saline and adrenaline is a useful option in lipoharvesting for autologous fat grafting. This report presents the case of 34-year-old woman who experienced inadvertent subcutaneous injection of hypertonic saline solution during body fat harvesting.
N, Kerfant +3 more
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