Results 71 to 80 of about 782,423 (287)
Alleviation of the Effects of NaCl Salinity in Spinach (Spinacia oleracea L. var. All Green) Using Plant Growth Regulators [PDF]
Exposure to environmental stress due to salinity has been reported to result in adverse effects on the growth of plants. Studies have shown that the use of plant growth regulators (PGRs) has an ameliorative effect on plants grown under saline conditions.
Anjali Ratnakar, Aruna Rai
core
Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo. [PDF]
Myrtucommulone a nonprenylated acylphloroglucinol contained in the leaves of myrtle (Myrtus communis), has been reported to suppress the biosynthesis of eicosanoids by inhibition of 5-lipoxygenase and cyclooxygenase-1 in vitro and to inhibit the release ...
BRAMANTI P. +10 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Stress-induced reinstatement of nicotine preference requires dynorphin/kappa opioid activity in the basolateral amygdala [PDF]
UNLABELLED: The dynorphin (DYN)/kappa-opioid receptor (KOR) system plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substances of abuse.
Bruchas, Michael R +4 more
core +2 more sources
Biotechnology of water and salinity stress tolerance [PDF]
Drought and salinity are among the environmental factors that constrain agricultural productivity most dramatically. Classical breeding programs aiming to improve stress tolerance have been hampered by the multigenic nature of the trait and the seemingly scarce natural genetic variability in crop plants.
openaire +3 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The development of saline-alkaline tolerant fish species has received extensive attention as a strategy for expanding aquaculture into inland saline-alkaline waters to optimize land use efficiency.
Ran Xu +4 more
doaj +1 more source
Este trabalho foi desenvolvido em ambiente protegido objetivando avaliar o desempenho de cultivares de alface em condições de salinidade. O delineamento utilizado foi inteiramente casualizado, e os tratamentos foram distribuídos em esquema fatorial 5 x 5,
Francisco de A. de Oliveira +4 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
IntroductionDeveloping salt-tolerant crops is critical for utilizing saline soils in agriculture. Limonium bicolor, a recretohalophyte with epidermal salt glands, represents a valuable genetic resource for salt tolerance engineering.
Lu Sun +7 more
doaj +1 more source

