Results 61 to 70 of about 8,399,787 (287)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Journal of the Science of Food and Agriculture, 2019 BACKGROUND Arbuscular mycorrhizal (AM) fungi establish symbioses with most agricultural plants and improve growth under soil stress conditions. The objective of the present study was to evaluate the functional contribution of two AM fungal inocula (a ...
C. Santander +5 more
semanticscholar +1 more source
Ecotoxicology and Environmental Safety, 2021 Soil salinization seriously restricts the growth and yield of soybeans. However, little information is available on the early growth stages of soybeans which are subjected to the gibberellin biosynthesis inhibitor, prohexadione-calcium (Pro-Ca).
Nai-Jie Feng +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2011 Este trabalho foi desenvolvido em ambiente protegido objetivando avaliar o desempenho de cultivares de alface em condições de salinidade. O delineamento utilizado foi inteiramente casualizado, e os tratamentos foram distribuídos em esquema fatorial 5 x 5,
Francisco de A. de Oliveira +4 more
doaj +1 more source
Plant Biotechnology Journal, 2021 To isolate the genetic locus responsible for saline–alkaline stress tolerance, we developed a high‐throughput activation tagging‐based T‐DNA insertion mutagenesis method using the model rice (Oryza sativa L.) variety Kitaake. One of the activation‐tagged
Yu-Tong Liu +10 more
semanticscholar +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PlantsSoil salinization poses a significant threat to global agricultural productivity. Among crops, soybean (Glycine max), an important source of oil and protein, is more susceptible to salt stress compared to other major crops such as wheat (Triticum ...
Tingjia Dong +4 more
doaj +1 more source
Seed priming improves the germination and growth rate of melon seedlings under saline stress
Ciência Rural, 2019 : The germination and growth of melon (Cucumis melo L.) plants can be severely affected by excess salts in the soil or irrigation water; however, negative effects of salt stress can be attenuated using appropriate methods of seed priming.
C. E. da Silva Oliveira +5 more
semanticscholar +1 more source