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Cancer remains one of the leading causes of death, and early detection of this disease is crucial for increasing survival rates. Although cancer can be diagnosed following tissue biopsy, the biopsy procedure is invasive; liquid biopsy provides an alternative that is more comfortable for the patient.
Taichiro Nonaka, David T.W. Wong
openaire +5 more sources
Promising applications of human-derived saliva biomarker testing in clinical diagnostics
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness in substances, and the huge amount. Due to its direct anatomical connection with oral, digestive, and endocrine systems, clinical usage of saliva testing ...
Mengyuan Song+4 more
doaj +1 more source
Rheological properties of saliva substitutes containing mucin, carboxymethylcellulose or polyethylenoxide [PDF]
Apparent viscosities at different shear rates were measured for 3 types of saliva substitutes: (a) mucin-containing saliva; (b) substitutes based upon carboxymethylcellulose (CMC), and (c) solution of polyethylenoxide (PEO). The apparent viscosities were
's-Gravenmade, E.J.+4 more
core +8 more sources
DNA Methylation Changes in Human Papillomavirus-Driven Head and Neck Cancers
Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also reveals alterations in its methylation profile.
Chameera Ekanayake Weeramange+5 more
doaj +1 more source
Salivary micro RNAs as biomarkers for oropharyngeal cancer
Background Despite the rising incidence, particularly of the human papillomavirus (HPV)‐associated fraction of oropharyngeal cancer (OPC), there are no early detection methods for OPC.
Chameera Ekanayake Weeramange+10 more
doaj +1 more source
The salivary metatranscriptome as an accurate diagnostic indicator of oral cancer
Despite advances in cancer treatment, the 5-year mortality rate for oral cancers (OC) is 40%, mainly due to the lack of early diagnostics. To advance early diagnostics for high-risk and average-risk populations, we developed and evaluated machine ...
Guruduth Banavar+16 more
doaj +1 more source
Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of these cancers are of squamous cell origin (HNSCC).
Xiaomin Huang+7 more
doaj +1 more source
Saliva from obese individuals suppresses the release of aroma compounds from wine. [PDF]
BackgroundRecent evidence suggests that a lower extent of the retronasal aroma release correspond to a higher amount of ad libitum food intake. This has been regarded as one of the bases of behavioral choices towards food consumption in obese people.
Chambery, Angela+11 more
core +7 more sources
Stimulated Parotid Saliva Is a Better Method for Depression Prediction
Background: Saliva cortisol is considered to be a biomarker of depression prediction. However, saliva collection methods can affect the saliva cortisol level.
Yangyang Cui+6 more
doaj +1 more source