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Promising applications of human-derived saliva biomarker testing in clinical diagnostics

open access: yesInternational Journal of Oral Science, 2023
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness in substances, and the huge amount. Due to its direct anatomical connection with oral, digestive, and endocrine systems, clinical usage of saliva testing ...
Mengyuan Song   +4 more
doaj   +2 more sources

Saliva as a Candidate for COVID-19 Diagnostic Testing: A Meta-Analysis

open access: yesFrontiers in Medicine, 2020
Background: COVID-19 is a serious and potentially deadly disease. Early diagnosis of infected individuals will play an important role in stopping its further escalation. The present gold standard for sampling is the nasopharyngeal swab method.
László Márk Czumbel   +2 more
exaly   +2 more sources

Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2

open access: yesEmerging Microbes and Infections, 2020
During the Coronavirus disease 2019 (COVID-19) pandemic, logistic problems associated with specimen collection limited the SARS-CoV-2 testing, especially in the community.
Jonathan Hon-Kwan Chen   +8 more
doaj   +2 more sources

Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis.

open access: yesJAMA Internal Medicine, 2021
Importance Nasopharyngeal swab nucleic acid amplification testing (NAAT) is the noninvasive criterion standard for diagnosis of coronavirus disease 2019 (COVID-19). However, it requires trained personnel, limiting its availability. Saliva NAAT represents
G. Butler-Laporte   +6 more
semanticscholar   +1 more source

A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma

open access: yesNature Biomedical Engineering, 2022
Rapid, accurate and frequent detection of the RNA of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and of serological host antibodies to the virus would facilitate the determination of the immune status of individuals who have Coronavirus ...
Devora Najjar   +15 more
semanticscholar   +1 more source

Consistent Detection of 2019 Novel Coronavirus in Saliva

open access: yesClinical Infectious Diseases, 2020
The 2019 novel coronavirus (2019-nCoV) was detected in the self-collected saliva of 91.7% (11/12) of patients. Serial saliva viral load monitoring generally showed a declining trend. Live virus was detected in saliva by viral culture.
K. To   +17 more
semanticscholar   +1 more source

Wax worm saliva and the enzymes therein are the key to polyethylene degradation by Galleria mellonella

open access: yesbioRxiv, 2022
Plastic degradation by biological systems with re-utilization of the by-products can be the future solution to the global threat of plastic waste accumulation.
A. Sanluis-Verdes   +17 more
semanticscholar   +1 more source

Rheological properties of saliva substitutes containing mucin, carboxymethylcellulose or polyethylenoxide [PDF]

open access: yes, 1984
Apparent viscosities at different shear rates were measured for 3 types of saliva substitutes: (a) mucin-containing saliva; (b) substitutes based upon carboxymethylcellulose (CMC), and (c) solution of polyethylenoxide (PEO). The apparent viscosities were
's-Gravenmade, E.J.   +4 more
core   +8 more sources

DNA Methylation Changes in Human Papillomavirus-Driven Head and Neck Cancers

open access: yesCells, 2020
Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also reveals alterations in its methylation profile.
Chameera Ekanayake Weeramange   +5 more
doaj   +1 more source

Salivary micro RNAs as biomarkers for oropharyngeal cancer

open access: yesCancer Medicine, 2023
Background Despite the rising incidence, particularly of the human papillomavirus (HPV)‐associated fraction of oropharyngeal cancer (OPC), there are no early detection methods for OPC.
Chameera Ekanayake Weeramange   +10 more
doaj   +1 more source

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