Results 31 to 40 of about 197,568 (264)

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

HUBUNGAN KADAR GULA DARAH PUASA TERHADAP KADAR PH DAN LAJU ALIRAN SALIVA PADA PENDERITA DIABETES MELLITUS TIPE 2 DI PUSKESMAS 1 KEMBARAN

Saintika Medika, 2018
Latar belakang: Diabetes Mellitus (DM) merupakan penyakit metabolik yang disebabkan oleh adanya defek sekresi insulin ataupun distribusi insulin. Indonesia masuk ke dalam urutan ke-4 besar kategori Top Ten Countries/Territories For Number Of Adults With ...
Arumita Puspa Hapsari, Refni Riyanto, Oke Kadarullah, Susiyadi Susiyadi   +3 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Construction and characterization of the Korean whole saliva proteome to determine ethnic differences in human saliva proteome. [PDF]

PLoS ONE, 2017
As the first step to discover protein disease biomarkers from saliva, global analyses of the saliva proteome have been carried out since the early 2000s, and more than 3,000 proteins have been identified in human saliva.
Ha Ra Cho, Han Sol Kim, Jun Seo Park, Seung Cheol Park, Kwang Pyo Kim, Troy D Wood, Yong Seok Choi   +6 more
doaj   +1 more source

Detection of SARS-CoV-2 Specific Antibodies in Saliva Samples

Frontiers in Immunology, 2022
Molecular assays on nasopharyngeal swabs act as a confirmatory test in coronavirus disease (COVID-19) diagnosis. However, the technical requirements of nasopharyngeal sampling and molecular assays limit the testing capabilities.
Siyang Yu, Siyang Yu, Peiyan Zhang, Mingfeng Liao, Juanjuan Zhang, Suisui Luo, Jinglei Zhai, Yaxi Zhang, Jingyan Lin, Jing Yuan, Zheng Zhang, Zheng Zhang, Fuxiang Wang, Lanlan Wei   +13 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

PERUBAHAN pH SALIVA SEBELUM DAN SESUDAH MENGKONSUMSI BUAH PISANG AYAM (Musa acuminata Colla) PADA MAHASISWA FKG UNSYIAH ANGKATAN 2014

Cakradonya Dental Journal, 2018
Saliva adalah cairan mulut yang kompleks yang merupakan gabungan dari berbagai cairan dan komponen yang diekskresikan ke dalam mulut. Potensial of hydrogen (pH) saliva merupakan derajat asam atau basanya suatu cairan tubuh yang dapat berubah karena ...
. Afrina, Santi Chismirina, Nura Shara Amirza   +2 more
doaj   +1 more source

Breastmilk-Saliva Interactions Boost Innate Immunity by Regulating the Oral Microbiome in Early Infancy. [PDF]

PLoS ONE, 2015
Xanthine oxidase (XO) is distributed in mammals largely in the liver and small intestine, but also is highly active in milk where it generates hydrogen peroxide (H2O2).
Saad S Al-Shehri, Christine L Knox, Helen G Liley, David M Cowley, John R Wright, Michael G Henman, Amitha K Hewavitharana, Bruce G Charles, Paul N Shaw, Emma L Sweeney, John A Duley   +10 more
doaj   +1 more source