Results 21 to 30 of about 587,936 (400)

Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs

medRxiv, 2020
Rapid and accurate SARS-CoV-2 diagnostic testing is essential for controlling the ongoing COVID-19 pandemic. The current gold standard for COVID-19 diagnosis is real-time RT-PCR detection of SARS-CoV-2 from nasopharyngeal swabs. Low sensitivity, exposure
A. Wyllie, John B. Fournier, A. Casanovas-Massana, M. Campbell, M. Tokuyama, P. Vijayakumar, B. Geng, M. C. Muenker, A. Moore, C. Vogels, M. Petrone, I. Ott, Peiwen Lu, Alice Lu-Culligan, Jonathan Klein, A. Venkataraman, Rebecca Earnest, Michael Simonov, R. Datta, Ryan Handoko, Nida Naushad, Lorenzo R. Sewanan, Jordan Valdez, Elizabeth B White, S. Lapidus, C. Kalinich, Xiaodong Jiang, Daniel J. Kim, Eriko Kudo, Melissa M. Linehan, Tianyang Mao, Miyu Moriyama, J. E. Oh, Annsea Park, Julio Silva, Eric Song, Takehiro Takahashi, M. Taura, Orr-El Weizman, P. Wong, Yexin Yang, S. Bermejo, C. Odio, Saad B. Omer, C. S. Dela Cruz, S. Farhadian, R. Martinello, Akiko Iwasaki, N. Grubaugh, Albert I. Ko   +49 more
semanticscholar   +1 more source

Saliva from obese individuals suppresses the release of aroma compounds from wine. [PDF]

, 2014
BackgroundRecent evidence suggests that a lower extent of the retronasal aroma release correspond to a higher amount of ad libitum food intake. This has been regarded as one of the bases of behavioral choices towards food consumption in obese people.
Chambery, Angela, Cutolo, Pier Paolo, Ercolini, Danilo, Esposito, Silvia, Genovese, Alessandro, Gilbert, Jack A, Moio, Luigi, Moneta, Elisabetta, Owens, Sarah M, Piombino, Paola, Severino, Valeria, Smith, Daniel P   +11 more
core   +7 more sources

Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers

eLife, 2021
Here, we develop a simple molecular test for SARS-CoV-2 in saliva based on reverse transcription loop-mediated isothermal amplification. The test has two steps: (1) heat saliva with a stabilization solution and (2) detect virus by incubating with a ...
Qing Yang, Nicholas R Meyerson, Stephen K Clark, Camille L Paige, Will T Fattor, Alison R Gilchrist, Arturo Barbachano-Guerrero, Benjamin G Healy, Emma R Worden-Sapper, Sharon S Wu, Denise Muhlrad, Carolyn J Decker, Tassa K Saldi, Erika Lasda, Patrick Gonzales, Morgan R Fink, Kimngan L Tat, Cole R Hager, Jack C Davis, Christopher D Ozeroff, Gloria R Brisson, Matthew B McQueen, Leslie A Leinwand, Roy Parker, Sara L Sawyer   +24 more
doaj   +1 more source

Clinical Evaluation of Self-Collected Saliva by Quantitative Reverse Transcription-PCR (RT-qPCR), Direct RT-qPCR, Reverse Transcription–Loop-Mediated Isothermal Amplification, and a Rapid Antigen Test To Diagnose COVID-19

Journal of Clinical Microbiology, 2020
The clinical performances of six molecular diagnostic tests and a rapid antigen test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were clinically evaluated for the diagnosis of coronavirus disease 2019 (COVID-19) in self-collected ...
M. Nagura-Ikeda, K. Imai, S. Tabata, K. Miyoshi, Nami Murahara, Tsukasa Mizuno, M. Horiuchi, Kento Kato, Yoshitaka Imoto, Makiko Iwata, S. Mimura, Toshimitsu Ito, Kaku Tamura, Y. Kato   +13 more
semanticscholar   +1 more source

Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection

Scientific Reports, 2021
We aimed to test the sensitivity of naso-oropharyngeal saliva and self-administered nasal (SN) swab compared to nasopharyngeal (NP) swab for COVID-19 testing in a large cohort of migrant workers in Singapore. We also tested the utility of next-generation
A. Teo, Y. Choudhury, I. Tan, C. Cher, Shi Hao Chew, Z. Wan, L. T. Cheng, L. Oon, M. Tan, K. Chan, L. Hsu   +10 more
semanticscholar   +1 more source

Possible proteomic biomarkers for the detection of pancreatic cancer in oral fluids

Scientific Reports, 2020
The 80% mortality rate of pancreatic-cancer (PC) makes early diagnosis a challenge. Oral fluids (OF) may be considered the ultimate body fluid for non-invasive examinations.
O. Deutsch, Y. Haviv, G. Krief, N. Keshet, R. Westreich, S. M. Stemmer, B. Zaks, S. P. Navat, R. Yanko, O. Lahav, D. J. Aframian, A. Palmon   +11 more
doaj   +1 more source

Saliva as a Noninvasive Specimen for Detection of SARS-CoV-2

Journal of Clinical Microbiology, 2020
Diagnostic testing for COVID-19 is central to controlling the global pandemic. ….
Eloise Williams, K. Bond, Bowen Zhang, M. Putland, D. Williamson   +4 more
semanticscholar   +1 more source

Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva

Journal of Korean medical science, 2020
Background Patients with coronavirus disease 2019 (COVID-19) can unknowingly spread the virus to several people during the early subclinical period. Methods We evaluated the viral dynamics in various body fluid specimens, such as nasopharyngeal swab ...
J. Yoon, Jung Yoon, J. Song, Soo-Young Yoon, C. Lim, Hye-Yeong Seong, J. Noh, H. Cheong, W. Kim   +8 more
semanticscholar   +1 more source

N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection

Nature Communications, 2021
The COVID-19 pandemic continues to have an unprecedented impact on societies and economies worldwide. There remains an ongoing need for high-performance SARS-CoV-2 tests which may be broadly deployed for infection monitoring.
D. Shan, Joseph M. Johnson, S. C. Fernandes, H. Suib, Soyoon Hwang, Danica Wuelfing, M. Mendes, M. Holdridge, E. M. Burke, K. Beauregard, Ying Zhang, M. Cleary, Samantha Xu, X. Yao, Purvish P. Patel, T. Plavina, David H. Wilson, Lei Chang, K. Kaiser, J. Nattermann, S. Schmidt, E. Latz, K. Hrusovsky, D. Mattoon, A. J. Ball   +24 more
semanticscholar   +1 more source

Disposable collection kit for rapid and reliable collection of saliva. [PDF]

, 2015
ObjectivesTo describe and evaluate disposable saliva collection kit for rapid, reliable, and reproducible collection of saliva samples.MethodsThe saliva collection kit comprised of a saliva absorbent swab and an extractor unit was used to retrieve whole ...
Shetty, Vivek, Takeda, Kazunori, Tezuka, Yuki, Yamaguchi, Masaki   +3 more
core   +1 more source