Results 1 to 10 of about 715,760 (390)
Nature Communications, 2022 Salivary glands that produce and secrete saliva, which is essential for lubrication, digestion, immunity, and oral homeostasis, consist of diverse cells. The long-term maintenance of diverse salivary gland cells in organoids remains problematic. Here, we
Yeo-Jun Yoon +12 more
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Bioengineering, 2023 Salivary gland dysfunction affects millions globally, and tissue engineering may provide a promising therapeutic avenue. This review delves into the current state of salivary gland tissue engineering research, starting with a study of normal salivary ...
Stephen C. Rose +3 more
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Salivary Gland Function, Development and Regeneration.
Physiological Reviews, 2022 Salivary glands produce and secrete saliva, which is essential for maintaining oral health and overall health. Understanding both the unique structure and physiological function of salivary glands, as well as how they are affected by disease and injury ...
A. M. Chibly +3 more
semanticscholar +1 more source
Management of Salivary Gland Malignancy: ASCO Guideline
Journal of Clinical Oncology, 2021 PURPOSE To provide evidence-based recommendations for practicing physicians and other healthcare providers on the management of salivary gland malignancy.
J. Geiger +16 more
semanticscholar +1 more source
Epithelial–immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis
Nature Reviews Rheumatology, 2021 In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland epithelium in pSS, including the nuclear factor-κB pathway, the ...
G. Verstappen +3 more
semanticscholar +1 more source
Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva
Journal of dentistry research, 2021 Although the physiological control of salivary secretion has been well studied, the impact of disease on salivary gland function and how this changes the composition and function of saliva is less well understood and is considered in this review ...
G. Proctor, A. Shaalan
semanticscholar +1 more source
The NF-κB pathway plays a vital role in rat salivary gland atrophy model
Heliyon, 2023 Objective: The aim of this study was to explore the histopathological and genetic changes in the submandibular glands after duct ligation and provide important clues to functional regeneration.
Yang Yang +5 more
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The evolving definition of salivary gland stem cells
npj Regenerative Medicine, 2021 Dysfunction of the salivary gland and irreversible hyposalivation are the main side effects of radiotherapy treatment for head and neck cancer leading to a drastic decrease of the quality of life of the patients.
C. Rocchi, L. Barazzuol, R. Coppes
semanticscholar +1 more source
Dietary nitrate supplementation prevents radiotherapy-induced xerostomia
eLife, 2021 Management of salivary gland hypofunction caused by irradiation (IR) therapy for head and neck cancer remains lack of effective treatments. Salivary glands, especially the parotid gland, actively uptake dietary nitrate and secrete it into saliva.
Xiaoyu Feng +15 more
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Molecular mechanisms of cellular metabolic homeostasis in stem cells
International Journal of Oral Science, 2023 Many tissues and organ systems have intrinsic regeneration capabilities that are largely driven and maintained by tissue-resident stem cell populations.
Xiaoyu Li, Ou Jiang, Songlin Wang
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