Results 111 to 120 of about 49,253 (320)

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

open access: yesBiological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye   +4 more
wiley   +1 more source

Candida albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5

open access: yesPathogens, 2015
Salivary Histatin 5 (Hst 5) is an antimicrobial peptide that exhibits potent antifungal activity towards Candida albicans, the causative agent of oral candidiasis.
Sumant Puri   +6 more
doaj   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source

Insight into the sialome of the castor bean tick, Ixodes ricinus [PDF]

open access: yes, 2008
Background In recent years, there have been several sialome projects revealing transcripts expressed in the salivary glands of ticks, which are important vectors of several human diseases.
Jindřich Chmelař   +5 more
core   +2 more sources

Progress of metabolomics‐centric multi‐omics research in medicine

open access: yesiMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang   +6 more
wiley   +1 more source

Are ticks venomous animals? [PDF]

open access: yes, 2017
[Introduction]: As an ecological adaptation venoms have evolved independently in several species of Metazoa. As haematophagous arthropods ticks are mainly considered as ectoparasites due to directly feeding on the skin of animal hosts. Ticks are of major
Cabezas-Cruz, Alejandro   +1 more
core   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

open access: yesiNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang   +9 more
wiley   +1 more source

A Recurrent Motif: Diversity and Evolution of ShKT Domain Containing Proteins in the Vampire Snail Cumia reticulata

open access: yesToxins, 2019
Proteins of the ShK superfamily are characterized by a small conserved domain (ShKT), first discovered in small venom peptides produced by sea anemones, and acting as specific inhibitors of voltage-dependent and calcium-activated K+ channels.
Marco Gerdol   +5 more
doaj   +1 more source

Evaluation of Aglianico grape skin and seed polyphenols astringency by SDS-PAGE electrophoresis of salivary proteins after the binding reaction [PDF]

open access: yes, 2006
SDS–PAGE electrophoresis and densitometry analysis were carried out to evaluate the reactivity of Aglianico red grape skin and seed polyphenols with human salivary proteins in order to find a method able to assess their astringency.
GAMBUTI, Angelita   +3 more
core  

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors [PDF]

open access: yes, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Kauferstein, Silke   +8 more
core   +3 more sources

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