The effect of non‐surgical periodontal treatment on progranulin levels
Abstract Background The aim of this study was to study the effect of non‐surgical periodontal therapy (NSPT) on gingival crevicular fluid (GCF) and serum progranulin (PGRN) levels in the early healing phases. Methods The study included periodontitis (test) (n = 24) and periodontal health (control) (n = 24) groups.
Aysegul Sari +2 more
wiley +1 more source
Around the first years of 2000, our teams, at the Cagliari and Catholic-Policlinico Gemelli (Rome) Universities, started an investigation of the intact proteins of human saliva by a top-down pipeline.
Tiziana Cabras +23 more
doaj +1 more source
Salivary Antimicrobial Peptides in Early Detection of Periodontitis
In the pathogenesis of periodontitis, an infection-induced inflammatory disease of the tooth-supporting tissues, there is a complex interaction between the subgingival microbiota and host tissues.
G. Güncü +3 more
semanticscholar +1 more source
Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein [PDF]
We recently described the Palate Lung Nasal Clone (PLUNC) family of proteins as an extended group of proteins expressed in the upper airways, nose and mouth.
A Walz +41 more
core +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos +8 more
wiley +1 more source
Potential protein biomarkers for burning mouth syndrome discovered by quantitative proteomics. [PDF]
Burning mouth syndrome (BMS) is a chronic pain disorder characterized by severe burning sensation in normal looking oral mucosa. Diagnosis of BMS remains to be a challenge to oral healthcare professionals because the method for definite diagnosis is ...
Diep, Cynthia +6 more
core +2 more sources
Ocular facial myositis and sialadenitis presenting with new onset ulcerative colitis
Abstract Extra‐intestinal manifestations of inflammatory bowel disease (IBD) can involve most organ systems, although the immunologic underpinnings are not well understood. Most patients who present with an extra‐intestinal manifestation have a single site of extra‐intestinal involvement; however, a small cohort presents with multiple different sites ...
Nicole Du, Nicole Mendez, Anil Darbari
wiley +1 more source
Increased expression and levels of human β defensins (hBD2 and hBD4) in adults with dental caries
Introduction: Defensins are small anti-microbial peptides produced by epithelial cells. These peptides have a broad range of actions against microorganisms, including Gram-positive and Gram-negative bacteria.Human defensins are classifi ed into two ...
Girolamo Jose Barrera +4 more
doaj +3 more sources
Can trigeminal sensations impact saltiness perception? A mini‐review
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan +2 more
wiley +1 more source

