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Potential uses of human salivary protein and peptide analysis in the diagnosis of disease

Archives of Oral Biology, 2012
Saliva is an important body fluid containing a complex mixture of proteins, peptides and other substances. These are not only important in maintaining the health of the oral cavity but also may yield information about oral and systemic disease. Comprehensive analysis and identification of the proteomic content of human saliva may contribute to the ...
Kawas, S.A.   +2 more
openaire   +3 more sources

Salivary proteins and peptides in the aetiology of caries in children: Systematic literature review

Oral Diseases, 2018
AbstractBackgroundTo assess the relationship of chosen salivary proteins and peptides levels with the occurrence of caries in children.MethodsPubMed, MEDLINE and EMBASE databases from 2000 to 2018 were researched for original observational studies published in English.
Paula Piekoszewska‐Ziętek   +2 more
openaire   +2 more sources

Presence of salivary Protein C and salivary peptide P-C-like immunoreactivity in the laryngo-tracheo-bronchial glands

Acta Endocrinologica, 1985
Abstract. An indirect immunofluorescence technique using antisera aganist salivary peptide P-C and against salivary Protein C was carried out on the laryngeal, tracheal and bronchial glands to examine whether salivary peptide P-C-like immunoreactivity, recently demonstrated in the serous cells of the human salivary glands, was also present in those of ...
S, Ito   +6 more
openaire   +2 more sources

The Amino Acid Sequence of a Salivary Proline-Rich Peptide, P-C, and Its Relation to a Salivary Proline-Rich Phosphoprotein, Protein C

The Journal of Biochemistry, 1980
A basic proline-rich peptide, P-C, was isolated from human whole saliva and its amino acid sequence was determined to be Gly-Arg-Pro-Gln-Gly-Pro-Pro-Gln-Gln-Gly-Gly-His-Gln-Gln-Gly-Pro-Pro-Pro-Pro-Pro-Pro-Gly-Lys-Pro-Gln-Gly-Pro-Pro-Pro-Gln-Gly-Gly-Arg-Pro-Gln-Gly-Pro-Pro-Gln-Gly-Gln-Ser-Pro-Gln.
S, Isemura, E, Saitoh, K, Sanada
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Vasoactive intestinal peptide evoked secretion of fluid and protein from rat salivary glands and the development of supersensitivity

Acta Physiologica Scandinavica, 1983
Vasoactive intestinal peptide (VIP) injected intravenously was found to induce a flow of saliva from both the parotid and the submaxillary gland in the rat. The secretion was slow in onset. The amount of saliva secreted from the parotid gland was less than that from the submaxillary gland. Parotid saliva was very viscous.
J, Ekström, B, Månsson, G, Tobin
openaire   +2 more sources

Proteins and peptides of the salivary gland secretion of medicinal leeches Hirudo verbana, H. medicinalis, and H. orientalis

Biochemistry (Moscow), 2008
The protein and peptide composition of medicinal leech salivary gland secretion (SGS) was analyzed in preparations obtained in July from three species--Hirudo verbana, H. medicinalis, and H. orientalis. Two-dimensional electrophoresis (molecular mass 10-150 kD and pI 3-10) revealed no distinctions in the distribution of over 100 silver-stained proteins.
I P, Baskova   +7 more
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Protein secretion in salivary glands of cats in vivo and in vitro in response to vasoactive intestinal peptide

Acta Physiologica Scandinavica, 1990
In anaesthetized cats exogenous vasoactive intestinal peptide failed to elicit any secretion of saliva from the submandibular and parotid glands. However, protein release from both glands occurred in response to VIP in the presence of α‐ and β‐adrenoceptor blocking agents and was dose‐dependent.
J, Ekström, G, Tobin
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'Salivary peptide P-C' of human pancreatic B-cells shares only partly immunoreactivity with salivary peptide P-C indicating a new B-cell protein which is different from insulin

Acta Endocrinologica, 1989
Abstract. Salivary peptide P-C like immunoreactivity, originally isolated from human whole saliva has later been found in the human pancreatic B-cells. In the present work an indirect immunofluorescence technique using monoclonal antibodies against isolated salivary peptide P-C was applied to Bouin fixed pancreas and parotid glands to study the ...
S, Ito   +7 more
openaire   +2 more sources

Sensing and quantification of salivary beta-amyloid peptides and protein sequencing for the saliva of normal and AD patients

2015 IEEE SENSORS, 2015
Using salivary beta-amyloid peptides, the results to diagnose AD are briefly introduced. The quantity of AD peptides in the saliva of normal young man (nYM, normal elderly (nE) group and AD patients is measured in the range from very low concentration (∼pg/ml) to high concentration (∼ng/ml).
null Ki-Bong Song   +2 more
openaire   +1 more source

A Synthetic Peptide Based on a Natural Salivary Protein Reduces Demineralisation in Model Systems for Dental Caries and Erosion

International Journal of Peptide Research and Therapeutics, 2007
The salivary protein statherin is an inhibitor of spontaneous and secondary precipitation of hydroxyapatite (HAp). It is also detected in enamel pellicle. The N-terminal region of statherin is involved in its adsorption onto tooth surfaces, and, calcium binding. A peptide (StN21) was designed with a 21 amino acid sequence identical to the N-terminus of
Kosoric, Jelena   +3 more
openaire   +2 more sources

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