Results 11 to 20 of about 10,206 (212)

Mitigating End-Stage Fatigue: Acute Inhaled Salmeterol Preserves Sprint Power in Simulated Cycling. [PDF]

Scand J Med Sci Sports
ABSTRACT This study tested whether a single 100 μg inhalation of salmeterol enhances 12‐s sprint performance in both fresh and fatigued states in elite road cyclists. In a randomized crossover design, 16 well‐trained, non‐asthmatic male cyclists completed 2 trials 1 week apart. Participants inhaled either 100 μg salmeterol or placebo 1h before testing.
Merlini M, Staiano W, Angius L, Romagnoli M, Schena F, Dickinson J, Marcora S.   +6 more
europepmc   +2 more sources

Cost-Effectiveness Analysis of Treatments for Children With Uncontrolled Asthma Symptoms Despite Inhaled Corticosteroids. [PDF]

Pediatr Pulmonol
ABSTRACT Introduction There is uncertainty about the cost‐effectiveness of treatment options for children and adolescents with uncontrolled asthma despite inhaled corticosteroid (ICS) treatment. Methods A Markov state‐transition model was developed to simulate costs from the perspective of the National Health Service in the UK and health outcomes ...
Culeddu G, Cividini S, Sinha I, Donegan S, Rose K, Fulton O, Turner S, Smith CT, Hughes DA, EINSTEIN collaborative group.   +9 more
europepmc   +2 more sources

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra‐Long‐Acting β2‐Agonists Used for Asthma and COPD [PDF]

Pharmacol Res Perspect
ABSTRACT β‐agonists have been used in asthma for 120 years. There are two recent changes: ultra‐long‐acting agonists for COPD and new asthma guidelines recommending formoterol/ICS inhalers phasing out short‐acting salbutamol inhalers. Few studies directly compare the molecular pharmacological properties of short (salbutamol, terbutaline, fenoterol ...
Proudman R, Baker J.
europepmc   +2 more sources

Fluticasone/salmeterol reduces remodelling and neutrophilic inflammation in severe equine asthma

Scientific Reports, 2017
Asthmatic airways are inflamed and undergo remodelling. Inhaled corticosteroids and long-acting β2-agonist combinations are more effective than inhaled corticosteroid monotherapy in controlling disease exacerbations, but their effect on airway ...
Michela Bullone, Amandine Vargas, Yvonne Elce, James G. Martin, Jean-Pierre Lavoie   +4 more
doaj   +1 more source

COMPARATIVE ANALYSIS OF THE IN VITRO EQUIVALENCE OF METERED AEROSOL INHALERS CONDUCTED BY THE NEW GENERATION IMPACTOR

Педиатрическая фармакология, 2012
Aim. To compare in vitro the aerodynamic particle size distributions of original and generic inhalers, which contain both fluticasone (FP) and salmeterol (SM).Material and methods.
L. A. Trukhacheva, N. V. Gorpinchenko, S. P. Dementyev   +2 more
doaj   +1 more source

Cost-Effectiveness of Umeclidinium/Vilanterol versus Salmeterol/Fluticasone in Elderly Patients with Chronic Obstructive Pulmonary Diseases in China

International Journal of COPD, 2022
Ying Lan,1 Nan Yang,2 Yirong Wang,1 Yujie Yang,1 Min Xu,1 Qin He1 1Department of Pharmacy, The Third People’s Hospital of Chengdu, Chengdu, People’s Republic of China; 2West China School of Pharmacy, Sichuan University, Chengdu, People’s Republic of ...
Lan Y, Yang N, Wang Y, Yang Y, Xu M, He Q   +5 more
doaj  

Long-Acting β2 Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis

Frontiers in Pharmacology, 2022
Psoriasis is a chronic inflammatory disease that affects approximately 1%–5% of the population worldwide. Considering frequent relapse, adverse drug reactions, and large costs of treatment, it is urgent to identify new medications for psoriasis ...
Rui Xu, Rui Xu, Shi Feng, Shi Feng, Zhou Ao, Zhou Ao, Yingxiang Chen, Yingxiang Chen, Congping Su, Congping Su, Xiuling Feng, Qin Fu, Qin Fu, Xiaoyan Yang, Xiaoyan Yang   +14 more
doaj   +1 more source

Economic Evaluation of Umeclidinium/Vilanterol versus Umeclidinium or Salmeterol in Symptomatic Non-Exacerbating Patients with COPD from a UK Perspective Using the GALAXY Model

International Journal of COPD, 2021
Soham Shukla,1 Dhvani Shah,2 Alan Martin,3 Nancy A Risebrough,4 Robyn Kendall,5 Claus F Vogelmeier,6 Isabelle Boucot,3 Lee Tombs,7 Leif Bjermer,8 Paul W Jones,3 Edward Kerwin,9 Chris Compton,3 François Maltais,10 David A Lipson,11,12 Afisi S Ismaila1,13 ...
Shukla S, Shah D, Martin A, Risebrough NA, Kendall R, Vogelmeier CF, Boucot I, Tombs L, Bjermer L, Jones PW, Kerwin E, Compton C, Maltais F, Lipson DA, Ismaila AS   +14 more
doaj  

Effects of Salmeterol Xinafoate and Fluticasone Propionate on Immunological Activation of Human Cultured Mast Cells

Allergology International, 2006
Background: The clinical efficacy of combination therapy comprising a long acting β2-agonist (LABA) and corticosteroid is widely recognized for the treatment of adult asthma.
Hirotomo Akabane, Masayuki Murata, Masafumi Kubota, Eiji Takashima, Hiroyuki Tanaka, Naoki Inagaki, Michiaki Horiba, Hiroichi Nagai   +7 more
doaj   +1 more source

Resorcinol-, catechol- and saligenin-based bronchodilating β2-agonists as inhibitors of human cholinesterase activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
We investigated the influence of bronchodilating β2-agonists on the activity of human acetylcholinesterase (AChE) and usual, atypical and fluoride-resistant butyrylcholinesterase (BChE). We determined the inhibition potency of racemate and enantiomers of
Anita Bosak, Anamarija Knežević, Ivana Gazić Smilović, Goran Šinko, Zrinka Kovarik   +4 more
doaj   +1 more source