Results 121 to 130 of about 378,455 (346)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Application of the DIVA principle to Salmonella Typhimurium vaccines in pigs avoids interference with serosurveillance programmes [PDF]

, 2011
Salmonellosis is one of the most important bacterial zoonotic diseases in humans and Salmonella infections are often linked with the consumption of contaminated pork.
Boyen, Filip, Haesebrouck, Freddy, Leyman, Bregje, Pasmans, Frank, Van Parys, Alexander, Verbrugghe, Elin   +5 more
core  

Cu or Fe‐Exchanged Natural Clinoptilolite as Sustainable Light‐Assisted Catalyst for Water Disinfection at Near Neutral pH

ChemPlusChem, EarlyView.
Fe and Cu exchanged natural clinoptilolites are evaluated as heterogeneous photo‐Fenton catalysts for water disinfection under visible light, using E. coli as a model pathogen. Bacterial detection limit is reached in 2 h, with no regrowth observed.
Paula Prieto‐Laria, Pilar Fernández‐Ibáñez, A. Rabdel Ruiz‐Salvador, Inés Canosa, Amando Flores, Carlos Salameh, José Enrique Domínguez‐Santos, Nuria Ofelia Núñez, Menta Ballesteros, Tania Farías   +9 more
wiley   +1 more source

PHENOTIPIC AND GENOTIPIC CHARACTERIZATION OF SALMONELLA SPP ISOLATED FROM MOLLUSCAN SHELLFISH IN MARCHE REGION

Italian Journal of Food Safety, 2009
Salmonella enterica is a major epidemic cause of gastrointestinal infection worldwide. Although the animal host is believed to be the primary habitat of this specie, Salmonella is frequently isolated from water sources and it has been identified in ...
S. Fisichella, M. Pacioni, G. Blasi, E. Rocchegiani, M. Staffolani, M.B. Valli   +5 more
doaj   +1 more source

Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. [PDF]

, 2019
Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood.
Ferreira, Fernando, Guo, Betty P, Lebrilla, Carlito B, Lokken, Kristen L, Luxardi, Guillaume, Ma, Li, Maverakis, Emanual, Mogilner, Alex, Reid, Brian, Ryzhuk, Volodymyr, Sun, Yaohui, Sun, Yuxin, Xu, Gege, Zhao, Min, Zhu, Kan   +14 more
core   +2 more sources

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, EarlyView.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

Exploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye, Wenhua Huang, Shujuan Yu, Yan Guo, Peng Sun, Ziyuan Chen, Linhui Hao, Yan Zhang, Caixia Li, Yongqiang Jiang, Jun Wu, Li Zhu, Hengliang Wang, Chao Pan   +13 more
wiley   +1 more source

Veterinary Medicine Needs New Green Antimicrobial Drugs [PDF]

, 2016
Given that: (1) the worldwide consumption of antimicrobial drugs (AMDs) used in food-producing animals will increase over the coming decades; (2) the prudent use of AMDs will not suffice to stem the rise in human antimicrobial resistance (AMR) of animal ...
Adams, Aidara-Kane, Alvarez, Amidon, Andersson, Andremont, Andremont, Angulo, Ashbolt, Baquero, Bednorz, Bibbal, Bonomo, Brunton, Call, Centers for Disease Control and Prevention, Chantziaras, Chen, Cheng, Cheng, Collignon, DANMAP, de Jong, Dewulf, Duse, Dutil, Edlung, European Food Safety Authority, European Food Safety Authority, European Food Safety Authority, European Medicine Agency, European Medicines Agency, European Medicines Agency, Fairbrother, Food and Drug Administration, Foster, Hansen, Herrick, Heuer, Hofmann, Hojberg, Holman, Horowitz, Huang, Ito, Jacobsen, Kusama, Langlois, Lindecrona, Lipinski, Lipinski, Luo, Marshall, Metz, Midtlyng, Montanari, Naess, Nielsen, Nord, O’Brien, O’Connor, Panagiotidis, Phillips, Pijpers, Pollet, Rashid, Rashid, Ratz, Rioux, Roof, Rose, Sakaeda, Sarmah, Singer, Smith, Sparo, Stamey, Subbiah, Takenouchi, Taverne, Thiele-Bruhn, Tolls, Toutain, Toutain, Toutain, Toutain, Toutain, Trobos, Van Boeckel, van den Bogaard, van der Waaij, Wellington, Whitman, World Health Organisation, World Health Organisation, Yazdankhah, Yusof, Zhang   +97 more
core   +3 more sources

Research Progress Based on SpyTag/SpyCatcher Self‐Assembling Peptides and Their Applications in the Food Field

Food Bioengineering, EarlyView.
The formation of isopeptide bonds in the SpyTag/SpyCatcher system and its application in the food field ABSTRACT The SpyTag/SpyCatcher system is a modular protein assembly tool based on isopeptide bond‐mediated covalent conjugation, distinguished by mild reaction conditions, rapid ligation rate, and independence from exogenous enzymes or chemical ...
Meng‐meng Cai, Zi‐fu Ni, Zhong‐ke Sun, Xiao‐long Li, Zi‐hao Wang, Min Zhang, Cheng‐wei Li   +6 more
wiley   +1 more source

Recovery of Salmonella isolated from eggs and the commercial layer farms

Gut Pathogens, 2017
Background Salmonella is recognized as a common bacterial cause of foodborne diarrheal illness worldwide, and animal or its food products have been the most common vehicles of the Salmonella infections. This study aimed to investigate the distribution of
Mei Long, Hua Yu, Li Chen, Guoyan Wu, Siyue Zhao, Wenwen Deng, Shujuan Chen, Kang Zhou, Shuliang Liu, Li He, Xiaoling Ao, Yubao Yan, Menggen Ma, Hongning Wang, Margaret A. Davis, Lisa Jones, Bei Li, Anyun Zhang, Likou Zou   +18 more
doaj   +1 more source