Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model. [PDF]
A patient with high grade undifferentiated pleomorphic soft-tissue sarcoma from a striated muscle was grown orthotopically in the right biceps femoris muscle of mice to establish a patient-derived orthotopic xenograft (PDOX) model.
Bouvet, Michael+18 more
core +16 more sources
THE DYNAMICS OF ANTIMICROBIAL RESISTANCE OF Salmonella typhimurium ISOLATES. [PDF]
Salmonella typhimurium is the most common pathogen isolated in foodstuffs toxin infections. The development of antibiotic resistance in Salmonella typhimurium over the last twenty years is caused by an extensive application of some antibiotics. The study
Erleta Peqini+6 more
doaj +1 more source
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
The long external filament of bacterial flagella is composed of several thousand copies of a single protein, flagellin. Here, we explore the role played by lysine methylation of flagellin in Salmonella, which requires the methylase FliB.
Julia A. Horstmann+18 more
semanticscholar +1 more source
Gene ilvY of Salmonella typhimurium [PDF]
Evidence is presented for the existence in Salmonella typhimurium LT2 of the regulatory gene ilv Y. The Escherichia coli K-12 ilvY gene product is shown to complement a S. typhimurium ilvY mutation in vivo.
R O Burns, D L Blazey
openaire +3 more sources
Overproduction of Salmonella typhimurium peptidase T [PDF]
Pseudorevertants able to use L-leucyl-L-leucyl-L-leucine as a leucine source have been isolated from a Salmonella typhimurium strain carrying stable (nonreverting) mutations in pepN, pepA, and pepB. These strains carry mutations at a locus pto (peptidase T overproducer) tightly linked to pepT that cause an elevated expression of the tripeptidase ...
Kathryn L. Strauch+2 more
openaire +3 more sources
Bacterial biofilms, especially those associated with implanted medical devices, are difficult to eradicate. Curli amyloid fibers are important components of the biofilms formed by the Enterobacteriaceae family.
Sarah A. Tursi+10 more
semanticscholar +1 more source
Transport of trehalose in Salmonella typhimurium [PDF]
We have studied trehalose uptake in Salmonella typhimurium and the possible involvement of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) in this process. Two transport systems could recognize and transport trehalose, the mannose PTS and the galactose permease.
Hiskias G. Keizer+2 more
openaire +3 more sources
Whole-genome sequencing (WGS) is a valuable tool in research on foodborne pathogens. In this study, a total of 143 isolates of Salmonella serotypes Enteritidis, Typhimurium, and Heidelberg sourced from eggs and chickens were analyzed for their ...
Lijun Hu+6 more
doaj +1 more source
Crystal Structure and Functional Characterization of YjgK From Salmonella Typhimurium. [PDF]
ABSTRACT The YhcH/YjgK/YiaL (DUF386) family, widely conserved across bacterial species, is involved in essential cellular processes yet remains poorly characterized. YjgK from Salmonella enterica serovar Typhimurium has drawn attention because of its potential role in biofilm formation associated with metal homeostasis, which may be critical for ...
Choi SY+6 more
europepmc +2 more sources
Salmonella Typhimurium resides largely as an extracellular pathogen in porcine tonsils, independently of biofilm-associated genes csgA, csgD and adrA [PDF]
In European countries, Salmonella enterica subspecies enterica serovar Typhimurium (Salmonella Typhimurium) is the serovar most frequently isolated from slaughter pigs1.
Boyen, Filip+7 more
core +4 more sources