Results 221 to 230 of about 99,967 (276)

Tertiary Lymphoid Structures in Tuberculosis: Persistence, Protection, and Pathology

open access: yesImmunological Reviews, Volume 333, Issue 1, August 2025.
ABSTRACT Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a major public health burden responsible for over a million deaths each year. A deeper understanding of the mechanisms that balance protective immunity and immunopathology is essential for developing more effective therapeutics.
Tiphaine M. N. Camarasa   +3 more
wiley   +1 more source

The Flagellin‐Specific Chaperone FliS of Borrelia burgdorferi Controls the Cytoplasmic Pool of Flagellins at the Level of Translation Initiation, Secretion, and Proteolysis

open access: yesMolecular Microbiology, Volume 124, Issue 2, Page 173-187, August 2025.
FliS, a flagellin protein chaperon of the Lyme disease pathogen Borrelia burgdorferi , controls the cytoplasmic pool of flagellins (FlaB) at the level of translation initiation, secretion, and proteolysis. Deletion of fliS blocks FlaB secretion and translation initiation through a pattern‐switching mechanism of FliS‐FlaB‐FliW/CsrA.
Ching Wooen Sze   +6 more
wiley   +1 more source

Metabolic network reconstruction as a resource for analyzing Salmonella Typhimurium SL1344 growth in the mouse intestine. [PDF]

open access: yesPLoS Comput Biol
Vayena E   +6 more
europepmc   +1 more source

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley   +1 more source

Safety evaluation of d‐α‐tocopheryl polyethylene glycol‐1000 succinate (Vitamin E TPGS) as a food additive

open access: yesEFSA Journal, Volume 23, Issue 8, August 2025.
Abstract The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of d‐α‐tocopheryl polyethylene glycol‐1000 succinate (Vitamin E TPGS) as a new food additive to be used in several food categories as emulsifier. In 2007, the EFSA AFC Panel assessed TPGS as a source of tocopherol intended to be used in foods for
EFSA Panel on Food Additives and Flavourings (FAF)   +30 more
wiley   +1 more source

Safety of lacto‐N‐tetraose (LNT) produced by a derivative strain (Escherichia coli K‐12 MG1655 INB_LNT_01) of E. coli K‐12 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015/2283

open access: yesEFSA Journal, Volume 23, Issue 8, August 2025.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto‐N‐tetraose (LNT) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human‐identical milk oligosaccharide (HiMO) LNT, but it also contains lacto‐N ...
EFSA Panel on Nutrition   +30 more
wiley   +1 more source

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