Results 41 to 50 of about 1,357,190 (346)

An overview of techniques for multifold enhancement in solubility of poorly soluble drugs

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2019
Poor water solubility of newly discovered compounds has become the most common challenge in the drug development process. Indeed, poor solubility is considered as the root cause of failure of drug during drug development phases.
Ansari Mohammad Javed
doaj   +1 more source

Geomechanical Simulation of 3D Directional Borehole Circumference in Deep Composite Salt Formation [PDF]

open access: yesLithosphere
Composite salt formation is a high-quality caprock for oil and gas resources. The accident encountered in composite salt formation drilling is a big problem to be solved in the drilling process.
Shiyuan Li   +5 more
doaj   +1 more source

Piezoelectric effect and electroactive phase nucleation in self-standing films of unpoled PVDF nanocomposite films [PDF]

open access: yes, 2018
Novel polymer-based piezoelectric nanocomposites with enhanced electromechanical properties open new opportunities for the development of wearable energy harvesters and sensors.
Ballirano, Paolo   +6 more
core   +1 more source

Charge renormalization and phase separation in colloidal suspensions [PDF]

open access: yes, 2000
We explore the effects of counterion condensation on fluid-fluid phase separation in charged colloidal suspensions. It is found that formation of double layers around the colloidal particles stabilizes suspensions against phase separation.
A Diehl   +9 more
core   +1 more source

In-operando two-dimensional X-ray imaging of CO2 electrolyzer

open access: yesCarbon Future
Membrane-electrode assembly (MEA)-based electrochemical devices offer a promising pathway toward sustainable chemical production. However, achieving high-resolution in-operando characterization of an MEA cross-section remains a significant challenge.
Qiucheng Xu   +6 more
doaj   +1 more source

The geophysical importance of bubbles in the sea [PDF]

open access: yes, 1982
Present knowledge of the mechanisms for production and enrichment and film drops by bursting bubbles is summarized, with particular emphasis on the unsolved problems.
Cirpriano, R. J.
core   +1 more source

Potential of mean force and the charge reversal of rodlike polyions

open access: yes, 2005
A simple model is presented to calculate the potential of mean force between a polyion and a multivalent counterion inside a polyelectrolite solution. We find that under certain conditions the electrostatic interactions can lead to a strong attraction ...
Angelini TE   +12 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural Characterization and Pharmaceutical Evaluation of Telmisartan Hydrochloride Salts

open access: yesCrystals
Telmisartan is an anti-hypertensive drug that exhibits poor aqueous solubility. In this work, salt formation was utilized to address this issue. Three hydrochloride salts of telmisartan (TELHCl), a trihemihydrate hydrochloride salt (TELHCl-Hyd), and two ...
Yuda Prasetya Nugraha   +6 more
doaj   +1 more source

Salt-mediated multicell formation in Deinococcus radiodurans [PDF]

open access: yesJournal of Bacteriology, 1991
The highly radiation-resistant tetracoccal bacterium Deinococcus radiodurans exhibited a reversible multi-cell-form transition which depended on the NaCl concentration in the medium. In response to 0.8% NaCl addition into the medium, the pair/tetrad (designated 2/4) cells in a young culture grew and divided but did not separate and became 8-, 16-, and ...
F I, Chou, S T, Tan
openaire   +2 more sources

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