Results 91 to 100 of about 1,221,371 (389)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Radical-cation salts of BEDT-TTF with lithium tris(oxalato)metallate(III) [PDF]
, 2015 The first radical-cation salts in the extensive family (BEDT-TTF)x[(A)M(C2O4)3]·Guest containing lithium as the counter cation have been synthesized and ...
Akutsu, H +6 more
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Influence of salts of heavy metals on the structure of epiphyseal cartilage [PDF]
, 2007 Among the known unfavorable influences on the skeletal bone, there is reaction on epiphyseal cartilage of bones under the influence of salts of heavy metals in the organism.
Nwaogy, A. +4 more
core
FEBS Open Bio, EarlyView.We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui +5 more
wiley +1 more source
A short review of the evidence base for Dead Sea Salt topical treatment and balneotherapy for skin and joint pathologies [PDF]
, 2010 The beneficial influence of the Dead Sea and t he clinical benefits of its mineral salts in different illnesses were first documented by the ancient historian Josephus Flavius about 2000 years ago.
Grech, David
core
FEBS Open Bio, EarlyView.Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu +4 more
wiley +1 more source
Evaluation of the users value of salts against apple scab and powdery mildew for fruit production [PDF]
, 2008 The research was aimed at finding anti resistance strategies for Integrated fruit growing. As the salts tested may be approvable for organic farming, the trial results are also of value for the development of scab an mildew control strategies for ...
Creemers, P. +4 more
core
Rheological behaviour and spectroscopic investigations of cerium-modified AlO(OH)colloidal suspensions [PDF]
, 2011 The rheological behaviour of aqueous suspensions of boehmite (AlO(OH)) modified with different Ce-salts (Ce(NO3)3, CeCl3, Ce(CH3COO)3 and Ce2(SO4)3) was investigated at a fixed Ce/Al molar ratio (0.05).
Bleta, Rudina +3 more
core +2 more sources
Revista de Ciências Agrárias, 2010 La agricultura intensiva y las actividades mineras se encuentran entre las principales fuentes de contaminación del sue-lo ocasionando con frecuencia la acumulación en el mismo de sales solubles, nutrientes, metales pesados, etc., con la con ...
J. A. Hernández +3 more
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