Results 61 to 70 of about 908,610 (265)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Modified polyurethane foams for fuel-fire Patent [PDF]

open access: yes, 1970
Modification of polyurethanes with alkyl halide resins, inorganic salts, and encapsulated volatile and reactive halogen for fuel fire ...
Parker, J. A., Riccitiello, S. R.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Insight into the Structure and Properties of Novel Imidazole-Based Salts of Salicylic Acid

open access: yesMolecules, 2019
The preparation of new active pharmaceutical ingredient (API) multicomponent crystal forms, especially co-crystals and salts, is being considered as a reliable strategy to improve API solubility and bioavailability.
Inês C. B. Martins   +5 more
doaj   +1 more source

Geometrical frustration in the spin liquid beta'-Me3EtSb[Pd(dmit)2]2 and the valence bond solid Me3EtP[Pd(dmit)2]2 [PDF]

open access: yes, 2012
We show that the electronic structures of the title compounds predicted by density functional theory (DFT) are well described by tight binding models. We determine the frustration ratio, J'/J, of the Heisenberg model on the anisotropic triangular lattice,
Powell, B. J., Scriven, E. P.
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Formic acid enhances whole-plant mulberry silage fermentation by boosting lactic acid production and inhibiting harmful bacteria

open access: yesFrontiers in Microbiology
Mulberry has also been regarded as a valuable source of forage for ruminants. This study was developed to investigate the impact of four additives and combinations thereof on fermentation quality and bacterial communities associated with whole-plant ...
Lihong Hao   +20 more
doaj   +1 more source

Intra-body microwave communication through adipose tissue

open access: yesHealthcare Technology Letters, 2017
The human body can act as a medium for the transmission of electromagnetic waves in the wireless body sensor networks context. However, there are transmission losses in biological tissues due to the presence of water and salts.
Noor Badariah Asan   +8 more
doaj   +1 more source

INVESTIGATION OF ENVIRONMENTAL IMPACTS ON SANDSTONE BLOCKS AT LUXOR TEMPLE AND CONCEPTS FOR CONSERATION [PDF]

open access: yesJournal of the General Union of Arab Archaeologists, 2016
Sandstone blocks were used in the construction of Luxor temple. However, they, especialy cement materials, were at a great risk because of being affected by various deterioration factors.
Elashmawy Ahmed
doaj   +1 more source

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