Results 31 to 40 of about 2,515 (236)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Nagrada za spašavanje kao šteta na teretu : [prikaz presude]

Uporedno pomorsko pravo, 1992
Članak 3. Konvencije iz 1976. o ograničenju odgovornosti brodara za pomorske tražbine, koji izuzima tražbine s naslova spašavanja od ograničenja odgovornosti, primjenjuje se samo na spašavatelje.
Dorotea Ćorić
doaj  

Coupled Motion Response Analysis for Dynamic Target Salvage under Wave Action

Journal of Marine Science and Engineering
The strategic recovery of buoys is a critical task in executing deep-sea research missions, as nations extend their exploration of marine territories.
Gang Sun, Shengtao Chen, Hongkun Zhou, Fei Wan   +3 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Zaštita morskoga okoliša i odredbe nove konvencije o spašavanju, iz 1989.

Uporedno pomorsko pravo, 1990
Nova Međunarodna konvencija o spašavanju iz 1989. godine veliku pažnju posvećuje i zaštiti morskoga okoliša. Osobito su značajne odredbe čl.14., koje uvodeći tzv.
Ivo Grabovac
doaj  

Finite time trajectory tracking control for partial actuator failure of underwater salvage robot

Zhongguo Jianchuan Yanjiu
ObjectiveThis paper seeks to solve the problem of the partial failure of the actuator of an underwater salvage robot caused by a decrease in the shipborne power supply voltage or corrosion of the control system circuit.
Qiang ZHANG, Yu'an JIANG, Gaoyang GUO, Yan ZHANG   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Pomorskopravni institut uklanjanja podrtina - koncepcijska razmatranja i kritika pravnog uređenja u hrvatskom pomorskom pravu

Poredbeno Pomorsko Pravo, 2011
Autorice elaboriraju odgovore na pitanja koncepcijske prirode vezane uz institut uklanjanja podrtina. Nakon, detaljne analize i tumačenja relevantnih pojmova, komparativnom metodom proučavaju se i uspoređuju instituti vađenja potonulih stvari, uklanjanja
Adriana Vincenca Padovan, Vesna Skorupan Wolff   +1 more
doaj  

Studies of indigenous lithic procurement in Uruguay and their implications for Southern Cone archaeology

Journal of Lithic Studies, 2016
Being a territory with several minerals and rocks suitable for knapping and grinding, Uruguay offered a lithic-rich environment for past indigenous cultures in the Southern Cone of South America.
Arlys Nicolás Batalla
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source