Results 91 to 100 of about 20,124 (224)

Salvianolic Acid B Alleviates MAFLD by Targeting PPAR‐α: Mechanistic Insights From Network Pharmacology and Lipidomics

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Salvianolic acid B (SALB) is the major water‐soluble bioactive constituent of Salvia miltiorrhiza Bunge, a traditional Asian health‐promoting food, while its therapeutic potential and molecular mechanisms in the pathogenesis of MAFLD remain largely unclear.
Fengyan Huang, Chen Qiu, Danna Wang, Yuanying Ni, Zhuotao Fu, Linchun Fu, Chao Liang, Shangyi Huang, Zhitong Deng   +8 more
wiley   +1 more source

Dissection of the mechanism of traditional Chinese medical prescription-Yiqihuoxue formula as an effective anti-fibrotic treatment for systemic sclerosis [PDF]

, 2014
BACKGROUND: Systemic sclerosis (SSc) is a connective tissue fibrotic disease for which there is no effective treatment. Traditional Chinese Medicine (TCM), such as the Yiqihuoxue formula used in Shanghai TCM-integrated Hospital, has shown the efficacy of
Dongdong Chen, Haiyan Chu, Hejian Zou, Jin Yuan, Jiucun Wang, Li Jin, Ling Yu, Mengmeng Song, Qingmei Liu, Ting Wu, Wenyu Wu, Wenzhen Tu, Xiaodong Zhou, Yanyun Ma   +13 more
core   +2 more sources

Phenolic Profile and Biological Evaluation of Salvia ceratophylloides Ard.: A Novel Source of Rosmarinic Acid

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Among the various extraction techniques investigated, the methanolic ultrasound‐assisted extract (MGME‐UAE) of Micromeria graeca L exhibited the strongest bactericidal effect, selectively inhibiting Proteus mirabilis (inhibition zone 12.7 ± 0.6 mm; MIC = 6.25 mg/mL).
Douaa Bekkai, Natalizia Miceli, Maria Fernanda Taviano, Carmelo Coppolino, Francesco Cacciola, Luigi Mondello, Patrizia Trifilò   +6 more
wiley   +1 more source

Preparation of controlled porosity osmotic pump tablets for salvianolic acid and optimization of the formulation using an artificial neural network method

Acta Pharmaceutica Sinica B, 2011
In this paper controlled porosity osmotic pump tablets (CPOPT) for salvianolic acid (SA) were prepared and optimized with experimental design methods including an artificial neutral network (ANN) method. Three causal factors, i.e., drug, osmotic pressure
Wen-Jin Xu, Ning Li, Chong-kai Gao
doaj   +1 more source

Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions [PDF]

, 2006
Salvia miltiorrhiza (Labiatae, Laminaceae), danshen, is an annual sage mainly found in China and neighboring countries. The crude drug (dried root) and its preparations are currently used in China to treat patients suffering from heart attack, angina ...
Lien Eric, Yang Jun, Wang Rubin, Adams James   +3 more
core   +1 more source

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source

Synthesis of SMND-309, a derivate of salvianolic acid B

Synthetic Communications, 2017
(E)-2-(6-((E)-2-carboxyvinyl)-2,3-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl) acrylic acid, designated SMND-309, was synthesized starting from 2-hydroxy-3-methoxybenzaldehyde in 12 steps and with an overall yield of 44%. The synthetic key features were the conversion of aryl aldehyde into aryl acetic acid for one-carbon extended, the Perkin condensation ...
Wu, Kong, Song, Chan, Cui, Dong-Mei, Zhang, Chen   +3 more
openaire   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

Anti-atherosclerotic effects and molecular targets of salvianolic acids from Salvia miltiorrhiza Bunge

Frontiers in Pharmacology
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a traditional Chinese medication used extensively as a therapeutic agent against atherosclerosis (AS) because of its substantial cardiovascular protective properties as well
Qingzhi Liang, Xiaoqin Liu, Xin Xu, Zhengtao Chen, Ting Luo, Yi Su, Hongyan Xie, Hongyan Xie, Hong Gao, Hong Gao, Chunguang Xie, Chunguang Xie   +11 more
doaj   +1 more source

Ultrasonic-assisted activated carbon separation removing bacterial endotoxin from salvia miltiorrhizae injection

Ultrasonics Sonochemistry
Ultrasonic-assisted activated carbon separation (UACS) was first employed to improve product quality by regulating adsorption rate and removing bacterial endotoxin from salvia miltiorrhizae injection.
Cunyu Li, Shuwan Tang, Yangyang Xu, Fangmei Liu, Mingming Li, Xinglei Zhi, Yun Ma   +6 more
doaj   +1 more source