Results 91 to 100 of about 5,932,890 (256)

Chemical characterization and bioactive properties of two aromatic plants: Calendula officinalis L. (flowers) and Mentha cervina L. (leaves) [PDF]

, 2016
The chemical composition and bioactive properties of two plants (Calendula officinalis L. and Mentha cervina L.) were studied. Their nutritional value revealed a high content of carbohydrates and low fat levels, and very similar energy values.
Barros, Lillian, Calhelha, Ricardo C., Castro, María Ángeles, Ferreira, Isabel C.F.R., Garcia, Pablo A., Miguel, María, Pereira, Carla, Santos-Buelga, Celestino   +7 more
core   +1 more source

A Novel Mechanism of Salvianolic Acid B in Postmyocardial Infarction Cardiac Protection: PHB1‐Driven Raf‐ERK Pathway Activation Promotes Cardiomyocyte Mitosis

MedComm, Volume 7, Issue 5, May 2026.
SalB binds to the C‐terminal of PHB1/2 heterodimer, inducing a conformational change that enhances Raf‐ERK pathway activation via Akt‐mediated phosphorylation, thereby promoting cardiomyocyte mitosis. ABSTRACT Heart failure (HF) following myocardial infarction remains a leading cause of global morbidity and mortality, necessitating novel therapeutic ...
Ce Cao, Bo Ma, Jian Zhang, Lili Yang, Zixin Liu, Haoran Li, Jianshu Song, Keer Zhang, Lei Li, Jianhua Fu, Jianxun Liu   +10 more
wiley   +1 more source

Application of targeted liposomes-based salvianolic acid A for the treatment of ischemic stroke

Neurotherapeutics
Novel therapeutics for the treatment of ischemic stroke remains to be the unmet clinical needs. Previous studies have indicated that salvianolic acid A (SAA) is a promising candidate for the treatment of the brain diseases. However, SAA has poor absolute
Ming-Yan Yang, Yu Liu, Ya-Wen Yu, Bai-Fang Gong, Jian Ruan, H. Fan   +5 more
semanticscholar   +1 more source

Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis

Asian Journal of Pharmaceutical Sciences, 2022
Idiopathic pulmonary fibrosis (IPF) is a serious and fatal pulmonary inflammatory disease with an increasing incidence worldwide. The drugs nintedanib and pirfenidone, are listed as conditionally recommended drugs in the “Evidence-Based Guidelines for ...
Peng Lu, Jiawei Li, Chuanxin Liu, Jian Yang, Hui Peng, Zhifeng Xue, Zhidong Liu   +6 more
semanticscholar   +1 more source

Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin [PDF]

Scientific Reports, 2017
AbstractSalvianolic acid B is an antioxidative ingredient derived from Radix Salviae miltiorrhizae that has been widely used to treat liver diseases. However, the therapeutic mechanism underlying Salvianolic acid B has remained largely unknown. Our studies verified that Salvianolic acid B efficiently blocked mitochondrial deformation and dysfunction ...
Yunxia Liu, Yingying Hu, Qiukai E, Ji Zuo, Ling Yang, Wen Liu   +5 more
openaire   +2 more sources

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Orthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li, Chaoqun Feng, Haoyun Huang, Junwen Deng, Fei Yang, Rigao Chen   +5 more
wiley   +1 more source

Salvianolic Acid B Suppresses ER Stress-Induced NLRP3 Inflammasome and Pyroptosis via the AMPK/FoxO4 and Syndecan-4/Rac1 Signaling Pathways in Human Endothelial Progenitor Cells

Oxidative Medicine and Cellular Longevity, 2022
Mounting evidence demonstrates uncontrolled endoplasmic reticulum (ER) stress responses can activate the inflammasome, which generally results in endothelial dysfunction, a major pathogenetic factor of chronic inflammatory diseases such as ...
Yubo Tang, Qingde Wa, Longyun Peng, Yifan Zheng, Jie Chen, Xiao Chen, Xuenong Zou, Huangxuan Shen, Shuai Huang   +8 more
semanticscholar   +1 more source

Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine [PDF]

, 2014
published_or_final_versio
Chen, X, Chen, X, Deng, R, Shen, J
core   +1 more source

Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity [PDF]

Phytomedicine, 2014
Salvianolic acid A (Sal A), an important constituent of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the improvement of acute myocardial ischemia. However, its content is very low in RSM.
Hongrui, Xia, Longru, Sun, Hongxiang, Lou, M Mukhlesur, Rahman   +3 more
openaire   +2 more sources

Mycorrhizal fungi were more effective than zeolites in increasing the growth of non-irrigated young olive trees [PDF]

, 2020
Four soil treatments, consisting of two commercial mycorrhizal fungi, one zeolite and an untreated control, were arranged in a factorial design with two foliar fertilization treatments, a foliar spray and a control to study the effects of commercial ...
Arrobas, Margarida, Brito, Cátia, Correia, Carlos M., Gonçalves, Alexandre, Lopes, João Ilídio, Martins, Sandra, Raimundo, Soraia, Rodrigues, M.A., Silva, Ermelinda   +8 more
core   +1 more source