Results 201 to 210 of about 929,762 (263)

Synergism of salvianolic acid B and ginsenoside Rg1 magnifies the therapeutic potency against ischemic stroke. [PDF]

Neuroreport
Shen H, Zhang Y, Shao Y, Chen S, Yin P, Liu X, Wang L, Zhang L, Jin Y, Wang Y, Xing R, Cho K, Jiang B.   +12 more
europepmc   +1 more source

Functionalized biomimetic nanoparticles loaded with salvianolic acid B for synergistic targeted triple-negative breast cancer treatment. [PDF]

Mater Today Bio
Cheng N, Zhou Q, Jia Z, Mu Y, Zhang S, Wang L, Chen Y.   +6 more
europepmc   +1 more source

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Salvianolic acid A diminishes LDHA‐driven aerobic glycolysis to restrain myofibroblasts activation and cardiac fibrosis via blocking Akt/GSK‐3β/HIF‐1α axis

Phytotherapy Research, 2023
Myofibroblasts activation intensively contributes to cardiac fibrosis with undefined mechanism. Salvianolic acid A (SAA) is a phenolic component derived from Salvia miltiorrhiza with antifibrotic potency.
Renaguli Hailiwu, Hao Zeng, Meiling Zhan, Ting Pan, Hua Yang, Ping Li   +5 more
semanticscholar   +1 more source

Salvianolic acid A attenuates arsenic-induced ferroptosis and kidney injury via HIF-2α/DUOX1/GPX4 and iron homeostasis.

Science of the Total Environment, 2023
Arsenic (As) is a prevalent pollutant in the environment and causes a high frequency of kidney disease in areas of high arsenic contamination, but its pathogenic mechanisms have yet to be completely clarified.
Desheng Yang, Xinyu Xia, Shuhua Xi
semanticscholar   +1 more source

Salvianolic Acid A Relieves Cognitive Disorder after Chronic Cerebral Ischemia: Involvement of Drd2/Cryab/NF-κB Pathway.

Pharmacological Research, 2021
Chronic cerebral ischemia (CCI) refers to long-term hypoperfusion of cerebral blood flow with the main clinical manifestations of progressive cognitive impairment. The pathological mechanism of CCI is complex, and there is a lack of effective treatments.
Yujiao Yang, Junke Song, Nannan Liu, Guang-yi Wei, Sha Liu, Sen Zhang, Nan Jiang, Haiguang Yang, Guanhua Du   +8 more
semanticscholar   +1 more source

A novel aquaphotomics based approach for understanding salvianolic acid A conversion reaction with near infrared spectroscopy.

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2022
As a fast and non-destructive detection method, near infrared spectroscopy, mainly containing overtones and combinations, can be used to quantify the components with a concentration of ≥ 1% in the analytical sample.
Xiaoxiao Dong, Zeqi Chen, Jianyang Pan, Hai-bin Qu   +3 more
semanticscholar   +1 more source

Salvianolic acid A alleviated inflammatory response mediated by microglia through inhibiting the activation of TLR2/4 in acute cerebral ischemia-reperfusion.

Phytomedicine, 2021
BACKGROUND Toll-like receptor 2 and Toll-like receptor 4 (TLR2/4) on microglia have been found as important regulators in the inflammatory response during cerebral ischemia/reperfusion (I/R).
Y. Ling, Lushuai Jin, Quanxin Ma, Yu Huang, Qinqin Yang, Minli Chen, Qiyang Shou   +6 more
semanticscholar   +1 more source

Antiplatelet and antithrombotic activities of salvianolic acid A

Thrombosis Research, 2010
Salvianolic acid A (SAA), the water-soluble phenolic acids in Salvia miltiorrhiza, has shown the most potent bioactivities, including protection against cerebral lesion, defense from oxidative damage and improvement of remembrance. In the present study, we studied the antiplatelet and antithrombotic effects of a newly synthesized SAA with different ...
Hua-Ying, Fan, Feng-Hua, Fu, Ming-Yan, Yang, Hui, Xu, Ai-Hong, Zhang, Ke, Liu   +5 more
openaire   +2 more sources

A quality marker study on salvianolic acids for injection

Phytomedicine, 2018
The quality of Chinese medicine (CM) has being an active and challenging research area for CM. Prof. Chang-Xiao Liu et al first proposed the concept of quality marker (Q-Marker) for the quality evaluation and control on CM. This article describe the exploratory studies of Q-Marker in salvianolic acids for injection (SAI) based on this new concept.This ...
Wei, Li, Navaneethakrishnan, Polachi, Xiangyang, Wang, Yang, Chu, Yuan, Wang, Meng, Tian, Dekun, Li, Dazheng, Zhou, Shuiping, Zhou, Aichun, Ju, Yubo, Li, Yanjun, Zhang, Min, Chen, Luqi, Huang, Changxiao, Liu   +14 more
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Synthesis of (+)-salvianolic acid A from sodium Danshensu

Tetrahedron, 2018
Abstract (+)-Salvianolic acid A, one of the most active components in the traditional Chinese medicine Danshen, has been synthesized over 10 steps in 6.5% overall yield. Starting from inexpensive ortho-vanillin and sodium Danshensu (synthesized via asymmetric catalysis in our group), the process consists of the following: A Wittig reaction that gives
Kai Xu, Hao Liu, Delong Liu, Cheng Sheng, Jiefeng Shen, Wanbin Zhang   +5 more
openaire   +1 more source