Results 141 to 150 of about 16,703 (172)
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Bioavailability of salvianolic acid B in conscious and freely moving rats
International Journal of Pharmaceutics, 2006Salvianolic acid B is an herbal ingredient isolated from Salvia miltiorrhiza. The aim of this study was to apply an automated blood sampling system coupled to a simple liquid chromatographic system to determine the bioavailability of salvianolic acid B in stress-free rats.
Yu-Tse, Wu +5 more
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Effect of salvianolic acid B on nasal absorption in rats in situ
China Journal of Chinese Materia Medica, 2016This experiment focused on the effect of salvianolic acid B's nasal absorption characteristics in rats. In the study, HPLC determination of salvianolic acid B(SalB) in perfusion liquid was established to examine the SalB nasal irritation in different pH buffers and stability in nasal perfusion solution, and systematically study in vivo nasal absorption
Qiu, Du +7 more
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Current progress of research on pharmacologic actions of salvianolic acid B
Chinese Journal of Integrative Medicine, 2012As one of the main water-soluble composites of Radix Salviae, salvianolic acid B is a phenolic acid ingredient of the Chinese drug, which is rich content in the herb and has strong pharmaceutical activity. It is used to treat cardiocerebral vascular diseases, antagonize hepatic/renal fibrosis, prevent cancer, and promote stem cell proliferation and ...
Wei, Cao +5 more
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Chemical conversions of salvianolic acid B by decoction in aqueous solution
Fitoterapia, 2012Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous solution (200 mL) at pH 4.9 and the
Hyoung Jae, Lee +2 more
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Studies on the stability of salvianolic acid B as potential drug material
Phytochemical Analysis, 2011AbstractIntroduction – Salvianolic acid B (Sal B) is one of the major water‐soluble compounds isolated from the roots of Salvia miltiorrhiza, which is widely used as a traditional Chinese medicine. Although much research on the general stability of Sal B has been undertaken and reported, there is still a need for further study of the stability required
Li-Na, Zhou +6 more
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Journal of Food Science, 2014
Abstract Salvianolic acid A (Sal A) was considered to be the compound with highest activity in Salvia miltiorrhiza (danshen). Due to its low content in raw materials, many studies reported its preparation from salvianolic acid B (Sal B).
Shidong, Kan +3 more
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Abstract Salvianolic acid A (Sal A) was considered to be the compound with highest activity in Salvia miltiorrhiza (danshen). Due to its low content in raw materials, many studies reported its preparation from salvianolic acid B (Sal B).
Shidong, Kan +3 more
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Salvianolic Acid B Attenuates Hypertrophic Scar Formation In Vivo and In Vitro
Aesthetic Plastic Surgery, 2023Hypertrophic scars (HTSs) are a fibroproliferative disorder that occur following skin injuries. Salvianolic acid B (Sal-B) is an extractant from Salvia miltiorrhiza that has been reported to ameliorate fibrosis in multiple organs. However, the antifibrotic effect on HTSs remains unclear. This study aimed to determine the antifibrotic effect of Sal-B in
Chio-Hou, Chong +6 more
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Analytica Chimica Acta, 2008
Abstract Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) are water-soluble phenolic acids in Danshen extract and they have high medicinal value. A rapid and novel complex high-performance liquid chromatography (HPLC) method has been developed and validated for the simultaneous determination of Sal A and Sal B within 10 min.
Beibei Zhou, Jian Pan, Jia Wang
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Abstract Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) are water-soluble phenolic acids in Danshen extract and they have high medicinal value. A rapid and novel complex high-performance liquid chromatography (HPLC) method has been developed and validated for the simultaneous determination of Sal A and Sal B within 10 min.
Beibei Zhou, Jian Pan, Jia Wang
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[Protective mechanism of salvianolic acid B on blood vessels].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023Salvianolic acid B(Sal B) is the main water-soluble component of Salvia miltiorrhiza Bunge. Studies have found that Sal B has a good protective effect on blood vessels. Sal B can protect endothelial cells by anti-oxidative stress, inducing autophagy, inhibiting endoplasmic reticulum stress(ERS), inhibiting endothelial inflammation and adhesion molecule
Chun-Kun, Yang +6 more
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Mechanism of action of Salvianolic Acid B by module-based network analysis
Bio-Medical Materials and Engineering, 2014Salvianolic Acid B (Sal B) is one of the main medicinal ingredients of Radix Salvia miltiorrhiza (Danshen) and possesses a variety of pharmacological effects. The purpose of this study was to discover the new mechanism of action of Sal B based on the protein interaction network (PIN) analysis.
Zhenzhen, Ren +6 more
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