Exploring the Mechanism of Salvianolic Acid B against Myocardial Ischemia-Reperfusion Injury Based on Network Pharmacology. [PDF]
Pharmaceuticals (Basel)Mao Q +7 more
europepmc +1 more source
Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis. [PDF]
Redox BiolFu Y +12 more
europepmc +1 more source
EXPRESSION OF CONCERN: Neuroprotective Mechanism of Salvianolic Acid B Against Cerebral Ischemia-Reperfusion Injury in Mice Through Downregulation of TLR4, p-p38MAPK, p-JNK, NF-κB, and IL-1β. [PDF]
Immun Inflamm Diseuropepmc +1 more source
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Bioavailability of salvianolic acid B in conscious and freely moving rats
International Journal of Pharmaceutics, 2006Salvianolic acid B is an herbal ingredient isolated from Salvia miltiorrhiza. The aim of this study was to apply an automated blood sampling system coupled to a simple liquid chromatographic system to determine the bioavailability of salvianolic acid B in stress-free rats.
Yu-Tse Wu, Tung-Hu Tsai, Ming-Shi Shiao
exaly +3 more sources
Salvianolic acid B (SalB) is an active component isolated from Chinese herbal medicine Salvia miltiorrhiza. The aim of this study was to investigate the extent of absolute oral bioavailability (F) of SalB in beagle dogs and the effect on blood viscosity after intravenous and oral administration of Salvianolic acids (SAs). A gradient elution HPLC method
Dong-Yan, Gao +4 more
openaire +2 more sources
Salvianolic acid B and lithospermic acid B are the major components of Salvia miltiorrhiza, which is one of the most popular herbal traditional medicines in Asian countries. Salvianolic acid B and lithospermic acid B are reported to have identical structures except for the configurational assignments of two stereocenters.
Anja, Watzke +3 more
openaire +2 more sources
Effect of sodium caprate on the oral absorptions of danshensu and salvianolic acid B
International Journal of Pharmaceutics, 2009The current study aims to investigate the effect of sodium caprate on the intestinal absorption and bioavailabilities of danshensu and salvianolic acid B, the major active components in Salvia miltiorrhiza Bge (Danshen). Biopharmaceutics and pharmacokinetics properties of the two compounds have been characterized by in vitro, in situ models as well as ...
Zhong Zuo, Moses S S Chow
exaly +3 more sources
Effect of salvianolic acid B on nasal absorption in rats in situ
China Journal of Chinese Materia Medica, 2016This experiment focused on the effect of salvianolic acid B's nasal absorption characteristics in rats. In the study, HPLC determination of salvianolic acid B(SalB) in perfusion liquid was established to examine the SalB nasal irritation in different pH buffers and stability in nasal perfusion solution, and systematically study in vivo nasal absorption
Qiu, Du +7 more
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Salvianolic Acid B Attenuates Hypertrophic Scar Formation In Vivo and In Vitro
Aesthetic Plastic Surgery, 2023Hypertrophic scars (HTSs) are a fibroproliferative disorder that occur following skin injuries. Salvianolic acid B (Sal-B) is an extractant from Salvia miltiorrhiza that has been reported to ameliorate fibrosis in multiple organs. However, the antifibrotic effect on HTSs remains unclear. This study aimed to determine the antifibrotic effect of Sal-B in
Chio-Hou, Chong +6 more
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Chemical conversions of salvianolic acid B by decoction in aqueous solution
Fitoterapia, 2012Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous solution (200 mL) at pH 4.9 and the
Hyoung Jae, Lee +2 more
openaire +2 more sources