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Preparation of salvianolic acid A by the degradation reaction of salvianolic acid B in subcritical water integrated with pH-zone-refining counter-current chromatography

Journal of Chromatography A, 2016
Salvianolic acid A is the major bioactive compound in Danshen, however, due to the chemical instability and low content in Danshen, it is difficult to extract amount of salvianolic acid A. Therefore, this study was to establish an effective strategy for obtaining adequate amount of salvianolic acid A, subcritical water extraction was used to degrade ...
Yan Cheng, Xiao Wang, Jia Li
exaly   +3 more sources

Salvianolic acid B ameliorates CNS autoimmunity by suppressing Th1 responses

Neuroscience Letters, 2016
Experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), is a Th1 and Th17 cell-mediated CNS autoimmune disease. Therefore, immune regulation is a key target for therapy. Salvianolic acid B (Sal B) is a major water-soluble bioactive component of the famous traditional Chinese medicine Salvia miltiorrhiza, which is ...
Zhihui, Dong   +4 more
openaire   +2 more sources

[Research on Molecular Spectra of Interactions Between Salvianolic Acid A and Salvianolic Acid B with Insulin, and Effect of Glucose on the Binding].

Guang pu xue yu guang pu fen xi = Guang pu, 2018
The interactions of Salvianolic acis A (SAA) and Salvianolic acid B (SAB) with insulin were studied by using fluorescence spectroscopy, UV-vis spectroscopy and ATR-FTIR spectroscopy in simulating physiological condition (pH 7.40). The fluorescence quenching of insulin by SAA and SAB were static quenching process.
Wen-yue, Yang   +7 more
openaire   +1 more source

[Removal of the colloidal impurities in the purification of salvianolic acid B].

Se pu = Chinese journal of chromatography, 2010
The removal of the colloidal impurities in the purification of salvianolic acid B (SB) was carried out on a macroporous adsorption resin column with a modified elution method on the principle of combining frontal chromatography with displacement chromatography.
Fan, Yang, Kejiang, He, Ke, Liu
openaire   +1 more source

Isolation and purification of salvianolic acid A and salvianolic acid B from by high-speed counter-current chromatography and comparison of their antioxidant activity

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2009
Yin-Shi Sun, Zhengbo Liu
exaly  

Investigation on ultrasound-assisted extraction of salvianolic acid B from root

Ultrasonics Sonochemistry, 2010
Zongsuo Liang, Juane Dong
exaly  

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