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Reassignment of the Configuration of Salvianolic Acid B and Establishment of Its Identity with Lithospermic Acid B

Journal of Natural Products, 2006
Salvianolic acid B and lithospermic acid B are the major components of Salvia miltiorrhiza, which is one of the most popular herbal traditional medicines in Asian countries. Salvianolic acid B and lithospermic acid B are reported to have identical structures except for the configurational assignments of two stereocenters.
Anja, Watzke   +3 more
openaire   +2 more sources

Current progress of research on pharmacologic actions of salvianolic acid B

Chinese Journal of Integrative Medicine, 2012
As one of the main water-soluble composites of Radix Salviae, salvianolic acid B is a phenolic acid ingredient of the Chinese drug, which is rich content in the herb and has strong pharmaceutical activity. It is used to treat cardiocerebral vascular diseases, antagonize hepatic/renal fibrosis, prevent cancer, and promote stem cell proliferation and ...
Wei, Cao   +5 more
openaire   +2 more sources

Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B

Food and Chemical Toxicology, 2008
Danshensu (3-(3,4-dihydroxyphenyl) lactic acid) and salvianolic acid B, two natural phenolic acids of caffeic acid derivatives isolated from Salvia miltiorrhiza root of the most widely used traditional Chinese medicine for the treatment of various cardiovascular diseases, have been reported to have potential protective effects from oxidative injury. To
Guang-Rong Zhao   +2 more
exaly   +3 more sources

Effect of sodium caprate on the oral absorptions of danshensu and salvianolic acid B

International Journal of Pharmaceutics, 2009
The current study aims to investigate the effect of sodium caprate on the intestinal absorption and bioavailabilities of danshensu and salvianolic acid B, the major active components in Salvia miltiorrhiza Bge (Danshen). Biopharmaceutics and pharmacokinetics properties of the two compounds have been characterized by in vitro, in situ models as well as ...
Moses S S Chow, Zhong Zuo
exaly   +3 more sources

Effect of salvianolic acid B on nasal absorption in rats in situ

China Journal of Chinese Materia Medica, 2016
This experiment focused on the effect of salvianolic acid B's nasal absorption characteristics in rats. In the study, HPLC determination of salvianolic acid B(SalB) in perfusion liquid was established to examine the SalB nasal irritation in different pH buffers and stability in nasal perfusion solution, and systematically study in vivo nasal absorption
Qiu, Du   +7 more
openaire   +2 more sources

Co-assembled Supramolecular Hydrogel of Salvianolic Acid B and a Phosphopeptide for Enhanced Wound Healing.

ACS Applied Materials and Interfaces, 2023
Supramolecular natural product gels (NPGs) have emerged as promising biomaterials for scalable and adjustable drug delivery systems. These gels possess biocompatibility, biodegradability, and the ability to mimic the extracellular matrix.
Xiaojing Huang   +7 more
semanticscholar   +1 more source

Chemical conversions of salvianolic acid B by decoction in aqueous solution

Fitoterapia, 2012
Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous solution (200 mL) at pH 4.9 and the
Hyoung Jae, Lee   +2 more
openaire   +2 more sources

Studies on the stability of salvianolic acid B as potential drug material

Phytochemical Analysis, 2011
AbstractIntroduction – Salvianolic acid B (Sal B) is one of the major water‐soluble compounds isolated from the roots of Salvia miltiorrhiza, which is widely used as a traditional Chinese medicine. Although much research on the general stability of Sal B has been undertaken and reported, there is still a need for further study of the stability required
Li-Na, Zhou   +6 more
openaire   +2 more sources

Transformation of Salvianolic Acid B to Salvianolic Acid A in Aqueous Solution and the In Vitro Liver Protective Effect of the Main Products

Journal of Food Science, 2014
Abstract Salvianolic acid A (Sal A) was considered to be the compound with highest activity in Salvia miltiorrhiza (danshen). Due to its low content in raw materials, many studies reported its preparation from salvianolic acid B (Sal B).
Shidong, Kan   +3 more
openaire   +2 more sources

Salvianolic acid B protects against UVB-induced HaCaT cell senescence and skin aging through NRF2 activation and ROS scavenging.

Journal of Photochemistry and Photobiology. B: Biology
BACKGROUND Prolonged sunlight exposure can cause skin photoaging. The epidermis, the outermost layer of the skin, protects the body from the environment.
Jia-Ming Sun   +10 more
semanticscholar   +1 more source

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