Results 51 to 60 of about 322,902 (281)

Fast Augmenting Paths by Random Sampling from Residual Graphs [PDF]

open access: yesSIAM Journal on Computing, 2015
Summary: Consider an \(n\)-vertex, \(m\)-edge, undirected graph with integral capacities and max-flow value \(v\). We give a new \(\tilde{O}(m + nv)\)-time maximum flow algorithm. After assigning certain special sampling probabilities to edges in \(\tilde{O}(m)\) time, our algorithm is very simple: repeatedly find an augmenting path in a random sample ...
Karger, David R., Levine, Matthew S.
openaire   +2 more sources

Sampling rare event energy landscapes via birth-death augmented dynamics

open access: yesPhysical Review E, 2023
17 pages, 5 ...
Benjamin Pampel   +3 more
openaire   +4 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Side-Scan Sonar Image Augmentation Method Based on CC-WGAN

open access: yesApplied Sciences
The utilization of deep learning algorithms for side-scan sonar target detection is impeded by the restricted quantity and representativeness of side-scan sonar (SSS) samples.
Junhui Zhu   +4 more
doaj   +1 more source

DOPING: Generative Data Augmentation for Unsupervised Anomaly Detection with GAN

open access: yes, 2018
Recently, the introduction of the generative adversarial network (GAN) and its variants has enabled the generation of realistic synthetic samples, which has been used for enlarging training sets.
Cheung, Ngai-Man   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

TADA: phylogenetic augmentation of microbiome samples enhances phenotype classification [PDF]

open access: yesBioinformatics, 2019
AbstractMotivationLearning associations of traits with the microbial composition of a set of samples is a fundamental goal in microbiome studies. Recently, machine learning methods have been explored for this goal, with some promise. However, in comparison to other fields, microbiome data are high-dimensional and not abundant; leading to a high ...
Sayyari, Erfan   +2 more
openaire   +2 more sources

Data Augmentation with Variational Autoencoders and Manifold Sampling [PDF]

open access: yes, 2021
We propose a new efficient way to sample from a Variational Autoencoder in the challenging low sample size setting. This method reveals particularly well suited to perform data augmentation in such a low data regime and is validated across various standard and real-life data sets.
Chadebec, Clément   +1 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

ECGAN: An Improved Conditional Generative Adversarial Network With Edge Detection to Augment Limited Training Data for the Classification of Remote Sensing Images With High Spatial Resolution

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
The classification of remote sensing images with high spatial resolution requires considerable training samples, but the process of sample making is slow and laborious.
Baikai Sui   +3 more
doaj   +1 more source

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