Results 51 to 60 of about 4,502,013 (256)
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Geomatics, Natural Hazards & RiskLandslide susceptibility mapping (LSM) commonly relies on the assumption of geographical similarity. However, existing sample augmentation methods assume global similarity and often overlook regional differences in landslide-forming mechanisms, limiting ...
Yuqian Yang +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The Effects of Mixed Sample Data Augmentation Are Class Dependent
IEEE AccessMixed Sample Data Augmentation (MSDA) techniques, such as Mixup, CutMix, and PuzzleMix, have been widely acknowledged for enhancing performance in a variety of tasks.
Haeil Lee, Hansang Lee, Junmo Kim
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
National Sample Survey (NSS) data (unit level)
The National Sample Survey contains a variety of socio-economic data for India and is collected by the Ministry of Statistics and Programme Implementation for planning and policy formulation.
National Sample Survey Office, Ministry of Statistics
core +2 more sources
Enhanced mixup for improved time series analysis
IJAIN (International Journal of Advances in Intelligent Informatics)Time series data analysis is crucial for real-world applications. While deep learning has advanced in this field, it still faces challenges, such as limited or poor-quality data.
Khoa Tho Anh Nguyen +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Analyzing Effects of Mixed Sample Data Augmentation on Model Interpretability
, 2023 Data augmentation strategies are actively used when training deep neural networks (DNNs). Recent studies suggest that they are effective at various tasks.
Kim, Seong Tae +2 more
core
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source