Results 231 to 240 of about 13,319,037 (325)

Toward a Correlative Metrology Approach on the Same 2D Flake: Graphene Oxide Case Study-Sample Preparation and Stability Issues. [PDF]

Nanomaterials (Basel)
Chibane L, Delvallée A, Fleurence N, Douri S, Morán-Meza J, Ulysse C, Piquemal F, Feltin N, Flahaut E.   +8 more
europepmc   +1 more source

Chromatin Immunoprecipitation (ChIP): Revisiting the Efficacy of Sample Preparation, Sonication, Quantification of Sheared DNA, and Analysis via PCR

, 2011
Pamela D. Schoppee Bortz, Brian R. Wamhoff   +1 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Sample Preparation for Multi-Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow. [PDF]

Proteomics
Woodland B, Farrell LA, Brockbals L, Rezcallah M, Brennan A, Sunnucks EJ, Gould ST, Stanczak AM, O'Rourke MB, Padula MP.   +9 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Immunoelectron microscopy: a comprehensive guide from sample preparation to high-resolution imaging. [PDF]

Discov Nano
Wu J, Su B, Gu L, Zhang J, Shi Q, Hu D.
europepmc   +1 more source

Sample Preparation and Fractionation of Arabidopsis thaliana Sperm and Vegetative Cell Nuclei by FACS

, 2015
Nina Chumak, Magdalena Mosiołek, Vera K. Schoft   +2 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Standardizing microbiome research: interlaboratory validation of SOPs for sample preparation and DNA extraction from food and environmental ecosystems. [PDF]

Environ Microbiome
Ferrocino I, Ferrara M, Garello M, Turchetti B, Andreolli M, Arena MP, Alduina R, Aloi F, Bevivino A, Bruno E, Capozzi V, Coronas R, De Vero L, Di Renzo T, Franzetti A, Gaglio R, Gallo G, Gullo M, Guarcello R, Giavalisco M, Lampis S, Mugnai G, Quatrini P, Reale A, Sbarra F, Sannino C, Spadaro D, Tatangelo V, Visca A, Zara G, Zotta T, Varese GC, Cocolin L.   +32 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source